نتایج جستجو برای: bacterial barrier

تعداد نتایج: 291925  

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005
Linda C H Yu Andrew N Flynn Jerrold R Turner Andre G Buret

Excessive apoptosis induced by enteric microbes leads to epithelial barrier defects. This mechanism has been implicated in the pathogenesis of inflammatory bowel diseases (IBD) and bacterial enteritis. The sodium-dependent glucose cotransporter (SGLT-1) is responsible for active glucose uptake in enterocytes. The aim was to investigate the effects of SGLT-1 glucose uptake on enterocyte apoptosi...

Journal: :Journal of endodontics 2001
G A Wolanek R J Loushine R N Weller W F Kimbrough K R Volkmann

This study evaluated the effectiveness of a dentin bonding agent as a barrier to prevent coronal microleakage and examined the effect of a eugenol-based sealer on the sealing ability of this resin adhesive. Fifty-one extracted human mandibular molars were incorporated in a model system using an oral streptococci as a microbial marker. Group 1 consisted of 15 teeth that were obturated with only ...

Journal: :Gut 2004
F Barreau L Ferrier J Fioramonti L Bueno

BACKGROUND Stressful events in the early period of life (for example, maternal deprivation) have been shown to modify adult immune and gastrointestinal tract functions. The present study aimed to establish whether maternal deprivation affects colonic epithelial barrier and the development of an experimental colitis in adult rats. METHODS Male Wistar rat pups were separated during postnatal da...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2015
Angelo Y Meliton Fanyong Meng Yufeng Tian Nicolene Sarich Gokhan M Mutlu Anna A Birukova Konstantin G Birukov

Increased endothelial cell (EC) permeability and vascular inflammation along with alveolar epithelial damage are key features of acute lung injury (ALI). Products of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine oxidation (OxPAPC) showed protective effects against inflammatory signaling and vascular EC barrier dysfunction induced by gram-negative bacterial wall lipopolysaccharide (L...

Journal: :The Journal of infectious diseases 2011
Ravi Maruvada Kwang Sik Kim

Neonatal meningitis by Eschericia coli RS218 occurs due to bacteremia and its transmigration across the blood-brain barrier. Although the outer membrane protein A (OmpA), a molecule with extracellular loops has been shown to contribute to the above phenomenon, we do not know the exact the role of these individual loops. Using bacterial strains whose individual loops have been removed, we demons...

Journal: :Current drug targets 2012
Daniel J Ericsson Alistair Standish Bostjan Kobe Renato Morona

The bacterial capsule is a recognized virulence factor in pathogenic bacteria. It likely works as an antiphagocytic barrier by minimizing complement deposition on the bacterial surface. With the continual rise of bacterial pathogens resistant to multiple antibiotics, there is an increasing need for novel drugs. In the Wzy-dependent pathway, the biosynthesis of capsular polysaccharide (CPS) is r...

Journal: :Cell 2006
Maeli Melotto William Underwood Jessica Koczan Kinya Nomura Sheng Yang He

Microbial entry into host tissue is a critical first step in causing infection in animals and plants. In plants, it has been assumed that microscopic surface openings, such as stomata, serve as passive ports of bacterial entry during infection. Surprisingly, we found that stomatal closure is part of a plant innate immune response to restrict bacterial invasion. Stomatal guard cells of Arabidops...

2011
Anirban Banerjee Brandon J. Kim Ellese M. Carmona Andrew S. Cutting Michael A. Gurney Chris Carlos Ralph Feuer Nemani V. Prasadarao Kelly S. Doran

Group B Streptococcus (GBS) is the leading cause of meningitis in newborn infants. Bacterial cell surface appendages, known as pili, have been recently described in streptococcal pathogens, including GBS. The pilus tip adhesin, PilA, contributes to GBS adherence to blood-brain barrier (BBB) endothelium; however, the host receptor and the contribution of PilA in central nervous system (CNS) dise...

Journal: :Journal of endodontics 2004
G Robert Lawley William G Schindler William A Walker David Kolodrubetz

The purpose of this study was to evaluate whether intracoronal delivery of an apical barrier of mineral trioxide aggregate (MTA) placed ultrasonically, non-ultrasonically, or ultrasonically with the addition of an intracanal composite resin provided a better seal against bacterial leakage. A second purpose was to determine whether intracanal composite resin or gutta-percha and sealer placed aga...

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