نتایج جستجو برای: background antimicrobial peptides with relative length 2

تعداد نتایج: 10328747  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Nannette Y Yount Michael R Yeaman

Conventional analyses distinguish between antimicrobial peptides by differences in amino acid sequence. Yet structural paradigms common to broader classes of these molecules have not been established. The current analyses examined the potential conservation of structural themes in antimicrobial peptides from evolutionarily diverse organisms. Using proteomics, an antimicrobial peptide signature ...

Journal: :PLoS ONE 2009
Dan Zhang Peiman Shooshtarizadeh Benoît-Joseph Laventie Didier André Colin Jean-François Chich Jasmina Vidic Jean de Barry Sylvette Chasserot-Golaz François Delalande Alain Van Dorsselaer Francis Schneider Karen Helle Dominique Aunis Gilles Prévost Marie-Hélène Metz-Boutigue

BACKGROUND Antimicrobial peptides derived from the natural processing of chromogranin A (CgA) are co-secreted with catecholamines upon stimulation of chromaffin cells. Since PMNs play a central role in innate immunity, we examine responses by PMNs following stimulation by two antimicrobial CgA-derived peptides. METHODOLOGY/PRINCIPAL FINDINGS PMNs were treated with different concentrations of ...

2014
Martin Malmsten

With increasing antibiotics resistance, there is an urgent need for novel infection therapeutics. Since antimicrobial peptides provide opportunities for this, identification and optimization of such peptides have attracted much interest during recent years. Here, a brief overview of antimicrobial peptides is provided, with focus placed on how selected hydrophobic modifications of antimicrobial ...

Journal: :Trends in microbiology 2000
R E Hancock G Diamond

Cationic antimicrobial peptides are found in all living species. A single animal can contain >24 different antimicrobial peptides, which fall into four structural classes. These peptides are produced in large quantities at sites of infection and/or inflammation and can have broad-spectrum antibacterial, antifungal, antiviral, antiprotozoan and antisepsis properties. In addition, they interact d...

2010
Kai Hilpert Brett McLeod Jessie Yu Melissa R. Elliott Marina Rautenbach Jochen Bürck Claudia Muhle-Goll Anne S. Ulrich Sandro Keller

Journal: :FEMS microbiology letters 2002
Robert E W Hancock Annett Rozek

Cationic amphiphilic peptides that are found throughout nature have very broad-spectrum activities against microbes. The initial sites of interaction are with microbial membranes. Although dogma suggests that their lethal action involves disruption of the cytoplasmic membranes, a number of cationic peptides can traverse intact membranes to interact with internal targets.

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علوم بهزیستی و توانبخشی - دانشکده توانبخشی 1393

abstract objectives gradual increase length and complexity of utterance (gilcu) therapy method is a form of operant conditioning. this type of treatment is very precise and controlled that is done in 54 steps in 3 speech situations consisted of monologue, reading and conversation. this study aimed to examine the effects of gilcu treatment method on reduction of speech dysfluency of school-age...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده علوم طبیعی 1391

in recent years many researchers have been focused on interaction of small molecules with dna. dna is generally the primary intracellular of anticancer drugs, so the interaction between small molecules and dna can cause dna damage in cancer cells, blocking the division of cancer cells and resulting in cell death. the flavonoids are a large group of polyphenolic natural products that are widely ...

Journal: :Journal of microbiology and biotechnology 2011
Hyungjae Lee Hae-Yeong Kim

Antimicrobial peptides exhibit high levels of antimicrobial activity against a broad range of spoilage and pathogenic microorganisms. Compared with bacteriocins produced by lactic acid bacteria, antimicrobial peptides from the genus Bacillus have been relatively less recognized despite their broad antimicrobial spectra. These peptides can be classified into two different groups based on whether...

2013
Lloyd Ryan Baptiste Lamarre Ting Diu Jascindra Ravi Peter J. Judge Adam Temple Matthew Carr Eleonora Cerasoli Bo Su Howard F. Jenkinson Glenn Martyna Jason Crain Anthony Watts Maxim G. Ryadnov

Antimicrobial or host defense peptides are innate immune regulators found in all multicellular organisms. Many of them fold into membrane-bound α-helices and function by causing cell wall disruption in microorganisms. Herein we probe the possibility and functional implications of antimicrobial antagonism mediated by complementary coiled-coil interactions between antimicrobial peptides and de no...

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