Abstract Continuous occurrence of heavy metals is a major cause environmental pollution due to its toxic effects. At minimum concentrations, these are highly reactive and can gather in the food chains web, causing dangers public health concerns. Soil samples were collected from Paharang drain, Faisalabad. Cadmium tolerant bacteria isolated evaluated for their MIC against Cd. The bacterial strai...

Bacterial spores are encased in a multilayered proteinaceous shell, called the coat. In many Bacillus spp., the coat protects against environmental assault and facilitates germination. In Bacillus anthracis, the spore is the etiological agent of anthrax, and the functions of the coat likely contribute to virulence. Here, we characterize a B. anthracis spore protein, called Cotbeta, which is enc...

A Bacillus strain producing a bacteriocin-like substance was characterized by biochemical profiling and 16S rDNA sequencing. Phylogenetic analysis indicated that the strain has high sequence similarity with Bacillus amyloliquefaciens. The antimicrobial substance was inhibitory to pathogenic and food-spoilage bacteria, such as Listeria monocytogenes, Bacillus cereus, Serratia marcescens, and Pas...

Bacillus cereus UW85 produces the linear aminopolyol antibiotic zwittermicin A (ZmA). This antibiotic has diverse biological activities, such as suppression of disease in plants caused by protists, inhibition of fungal and bacterial growth, and amplification of the insecticidal activity of the toxin protein from Bacillus thuringiensis. ZmA has an unusual chemical structure that includes a d ami...

Bacteriocin AS-48 showed high bactericidal activity for mesophilic and psychrotrophic strains of Bacillus cereus over a broad pH range. AS-48 inhibition of the enterotoxin-producing strain LWL1 was enhanced by sodium nitrite, sodium lactate, and sodium chloride. The latter also enhanced AS-48 activity against strain CECT 131. Bacterial growth and enterotoxin production by strain LWL1 were compl...

Anthrax, caused by Bacillus anthracis, is a fatal disease and all the warm bloodedanimals are susceptible to this disease. Many livestock populated areas in Pakistan endemic forAnthrax (Thappa Karthikeyan 2001), therefore population annually vaccinatedagainst Anthrax. Veterinary Research Institute (VRI) has been producing Anthrax Spore Vaccine(ASV) for couple of decades. The current study was d...

Phospholipase C (phosphatidylcholine cholinephosphohydrolase, EC 3.1.4.3) is a bacterial enzyme widely used in membrane and phospholipid studies. For such studies the highest possible degree of purity is required. Both the Bacillus cereus and the Clostridium perfringens enzymes have been purified to apparent homogeneity using conventional techniques [l-3]. However, using a phospholipase C-hyper...

Bacillus cereus (B. cereus) is a pathogen in opportunistic infections. Here we show that Bacillus cereus sphingomyelinase (Bc-SMase) is a virulence factor for septicemia. Clinical isolates produced large amounts of Bc-SMase, grew in vivo, and caused death among mice, but ATCC strains isolated from soil did not. A transformant of the ATCC strain carrying a recombinant plasmid containing the Bc-S...

The structure and regulation of the gab gene cluster, involved in -aminobutyric acid (GABA) shunt, were studied by characterizing gabT and gabD genes cloned from Bacillus thuringiensis. Deletions of the gabT and gabD genes in B. thuringiensis strain HD-73 did not affect the growth of mutant strains in rich culture media, but the growth of a gabT deletion mutant strain was reduced in basic media...