نتایج جستجو برای: b3 and c increased p005
تعداد نتایج: 16998856 فیلتر نتایج به سال:
Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no antiviral compounds currently exist to treat infections with these viruses. We screened the Prestwick Chemical Library, a library of approved drugs, for inhibitors of coxsackievirus B3, identified pirlindole as a potent novel inhibitor, and confirmed the inhibitory action of dibucaine, zuclopenthixol, fluoxetine...
Microdeletions in the azoospermia factor (AZF) regions on the long arm of the human Y chromosome are known to be associated with spermatogenic failure. Although AZFc is recurrently deleted in azoospermic or oligozoospermic males, no definitive conclusion has been reached for the contribution of different partial AZFc deletions to spermatogenic failure. To further investigate the roles of partia...
The human Y chromosome is replete with amplicons-very large, nearly identical repeats-which render it susceptible to interstitial deletions that often cause spermatogenic failure. Here we describe a recurrent, 1.8-Mb deletion that removes half of the azoospermia factor c (AZFc) region, including 12 members of eight testis-specific gene families. We show that this "b2/b3" deletion arose at least...
ions. Following SLAM, abstractions are represented by Boolean Programs. Unlike SLAM, the semantics of these programs is given via a variant of Mixed Transition Systems (MixTS) [7, 11]. Compared to Modal and 3-valued TSs, MixTSs allow for (a) 1: 2: 3: 4: 5: 6: 7: 8: 9: 10: 11: 12: 13: 14: 15: 16: 17: int p1,p2,p3,x,y; p1=p2=p3=x=y=5; if(p3<=0) return; if(y<0) {if(x>2){ if(y>10) {if(p2>0) ERROR;}...
The plasma-membrane integrin aIIbb3 (CD41/CD61, GPIIbIIIa) is a major functional receptor in platelets during clotting. A common isoform of integrin b3, Leu33Pro is associated with enhanced platelet function and increased risk for coronary thrombosis and stroke, although these findings remain controversial. To better understand the molecular mechanisms by which this sequence variation modifies ...
Our objective was to isolate a prelysosomal compartment involved in receptor-mediated endocytosis in human epidermoid carcinoma (A431) cells. The isolation protocol involves density modification of endosome elements in A431 cells, caused by the receptor-dependent binding and internalization at 20 degrees C of colloidal gold-transferrin receptor antibody (B3/25) particles. The use of 125I-labell...
abstract:assume that y is a banach space such that r(y ) ? 2, where r(.) is garc?a-falset’s coefficient. and x is a banach space which can be continuously embedded in y . we prove that x can be renormed to satisfy the weak fixed point property (w-fpp). on the other hand, assume that k is a scattered compact topological space such that k(!) = ? ; and c(k) is the space of all real continuous ...
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