CONTEXT Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the bowel (IBD) whose causes are not fully known. Emerging data indicate that alterations in cytokine synthesis may play a role in IBD pathogenesis. AIMS We aimed to determine the association between tumor necrosis factor-alfa (TNFα) promoter polymorphisms (at positions - 308 and - 1031) and suscepti...

BACKGROUND Brucellosis is an endemic infection in Georgia. We conducted a review of patient records with a suspected or confirmed diagnosis of brucellosis over three decades at the central referral hospital for brucellosis cases, the Institute of Parasitology and Tropical Medicine (IPTM) in Tbilisi. The purpose was to describe the demographic profile and clinical characteristics as well as diag...

conclusions the results demonstrated that the mortality rate was higher in cf patients with a positive family history, a consanguineous marriage, and residence in a rural area. therefore, demographic factors play an important role in the outcome of cystic fibrosis. unfortunately, these parameters, which can be managed easily and with low cost, have been overlooked. patients and methods this was...

Abstract Background Obesity is a health problem defined by surplus body fat accumulation and one of the leading causes morbidity mortality. Earlier studies indicated influence brain-derived neurotrophic factor ( BDNF ) molecular alterations in development obesity. One these variations G196A single nucleotide polymorphism (Val66Met; SNP rs6265), which impairs intracellular trafficking reduces se...

In today's globalized world integration of languages is a frequently experienced issue. Nowadays, people speak both English and Russian by mixing them with the Azeri language often. linguistics, this phenomenon two analyzed termed in various forms, such as code-switching, interculturalism, code-mixing etc. The study integrates quantitative research to assess interlocutors' respondents; attitude...