INTRODUCTION The aim of this study was to determine the effectiveness of intraocular injections of bevacizumab for neovascularisation of the iris and neovascular glaucoma. CLINICAL PICTURE Three patients with neovascularisation of the iris due to various causes were recruited. TREATMENT Patients were treated with intraocular bevacizumab. OUTCOME Neovascularisation of the iris was noted to...

Corneal avascularity is necessary for the preservation of optimal vision. The cornea maintains a dynamic balance between pro- and antiangiogenic factors that allows it to remain avascular under normal homeostatic conditions; however, corneal avascularity can be compromised by pathologic conditions that negate the cornea's "angiogenic privilege." The clinical relevance of corneal neovascularizat...

Aggressive posterior retinopathy of prematurity (formerly known as fulminate/type II/rush disease) occurs in zone 1 or posterior zone 2. Treatment involves extensive near confluent laser ablation of a large area of avascular retina. Anterior segment ischemia is a rare complication that can occur due to injury to the long posterior ciliary arteries in the horizontal meridians during aggressive p...

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Avastin, a widely used colon cancer drug manufactured by San Francisco-based biotech company Genentech, has proven a somewhat effective treatment for lung and breast cancer when administered at twice the normal dose. In February, the New York Times carried a story about Avastin's extraordinarily high price when used in this alternative way: $100,000 for one year's treatment--a figure fully twic...