Multiple sclerosis (MS) is an autoimmune, inflammatory disease characterized by demyelination and axonal degeneration in the central nervous system. MS is the second major cause of disability following trauma, and is mostly seen between the ages of 20 - 40 years and in women. Autoimmune hepatitis (AH) is a chronic disease characterized by hypergammaglobulinemia, high levels of transaminases, pr...

conclusions thyroid dysfunction was not higher in sle patients compared to healthy individuals. however, anti-tg antibodies were higher in sle patients. it has not yet been established that thyroid function tests should be performed routinely in sle patients. results the mean age of sle patients and controls were 32.16 ± 9.19 and 32.48 ± 9.47 years, respectively (p = 0.821). patients had signif...

Dear Editor, Sarcoidosis is a systemic granulomatous disease of unknown aetiology. It emerges in the form of hiler adenopathy and interstitial pulmonary disease in most cases. The lungs, eyes, skin, abdominal organs, central nerve system and bones are among the organs involved.1,2 Although non-caseous granulomas are detected histopathologically in the involvement of the liver in sarcoidosis, th...

Unusual cases of coexistence between Wilson's disease and autoimmune hepatitis have occurred. There are characteristics both diseases in this community patients, laboratory histo pathological findings can be misleading. Wilson disease's clinical appearance differ widely; thus,
 there is not always an easy diagnosis. In addition to being childhood young adult illnesses, also triggered at an...

Hepatitis a general term which refers to inflammation of the liver. It may result from various causes, both infectious ( viral, bacterial, fungal, and parasitic) noninfectious (alcohol, drugs, autoimmune diseases, metabolic diseases). The hepatitis B X protein (HBx) plays role in epigenetic regulation HBV replication. Real-time PCR has catalysed wider acceptance because it is more rapid, sensit...

Patients with autoimmune urticaria show a higher rate of seropositivity for other autoantibodies and often have a history of autoimmune conditions. They also tend to have more severe symptoms and to have a poor response to conventional antihistamine treatment. Autoimmune hepatitis is a chronic inflammatory disorder in which progressive liver injury is thought to be the result of a T-cell-mediat...

Autoimmune diseases are characterized by an exaggerated immune response leading to damage and dysfunction of specific or multiple organs and tissues. Most autoimmune diseases are more prevalent in women than in men. Symptom severity, disease course, response to therapy and overall survival may also differ between males and females with autoimmune diseases. Sex hormones have a crucial role in th...

BACKGROUND A primary characteristic of complex genetic diseases is that affected individuals tend to cluster in families (that is, familial aggregation). Aggregation of the same autoimmune condition, also referred to as familial autoimmune disease, has been extensively evaluated. However, aggregation of diverse autoimmune diseases, also known as familial autoimmunity, has been overlooked. There...

Myopathy, which clinically shows muscular pain (myalgia), weakness, cramps, stiffness and spasm, is one of neuromuscular disorders due to inflammation and/or dysfunction of muscle fibers. “Myositis”, which is a general term for inflammation of the muscle, is pathologically an inflammatory myopathy seen seen mainly in autoimmune disorders including dermatomyositis (DM). The myopathy is classifie...

Autoimmune liver diseases are different entities that sometimes have overlapping features. They share many of the general characteristics of autoimmune diseases, with systemic involvements. Here, we report a 30-year-old woman with ophthalmic symptoms of conjunctivitis and dacryocystitis who was treated completely. After a few months, the patient presented with autoimmune cholangiopathy. Sequela...