Over the last decade, a lot of papers have been published by scientists and clinicians in order to disseminate their knowledge about major steps accomplished in the research of autoimmune disorders and pregnancy. While pregnancy is delayed until later age in the majority of western countries and the incidence of autoimmune disorders, particularly rheumatic conditions, is increasing specifically...

OBJECTIVE Research suggests autoimmune processes to be involved in psychiatric disorders. We aimed to address the prevalence and incidence of autoimmune diseases in a large Finnish patient cohort with anorexia nervosa, bulimia nervosa, and binge eating disorder. METHODS Patients (N = 2342) treated at the Eating Disorder Unit of Helsinki University Central Hospital between 1995 and 2010 were c...

Vitiligo is an autoimmune skin disease which is characterized by depigmented patches due to loss of pigment cells. Evidence suggests that cell-mediated immunity plays a role in melanocyte destruction while some patients have antibodies to melanocytes or melanocytic proteins. Vitiligo is strongly associated with a number of autoimmune disorders. Autoimmune thyroiditis is the most prevalent disea...

guillain-barre syndrome is a neurologic disorder that may appear after infection or major surgery.  guillian-barre syndrome following cardiac surgery is rare and only based on case reports, and we review all of the published cases. a 52-year-old man after 5 months suffering from chest pain was referred to our hospital and underwent coronary artery bypass graft for 3 vessel disease. the patient ...

Background and aim: Melasma is an acquired, symmetric hyperpigmentation, specially in sun-exposed skin. Disorders of thyroid gland result from processes that stimulate the overproduction or underproduction of thyroid hormones. This study was performed to assess the association of melasma with thyroid disorders.Materials and Methods: This case-control study was performed...

The Wnt signaling pathway plays a key role in many biological aspects, such as cellular proliferation, tissue regeneration, embryonic development, and other systemic effects. Under a physiological condition, it is tightly controlled at different layers and arrays, and a dysregulated activation of this signaling has been implicated into the pathogenesis of various human disorders, including auto...

Immune-mediated neuromuscular disorders include pathologies of the peripheral nervous system, neuromuscular junction, and muscles. If overlap syndromes (or the association of almost two autoimmune disorders) are recognized, the simultaneous occurrence of several autoimmune neuromuscular disorders is rare. We describe two patients presenting the simultaneous occurrence of inflammatory neuropathy...