Over the last few decades, polymers and their composites have shown a lot of promises in providing more viable alternatives to surgical procedures that require scaffolds implants. With advancement biomaterial technologies, it is possible overcome limitations current methods, including auto-transplantation, xeno-transplantation, implantation artificial mechanical organs used treat musculoskeleta...

Autologous hematopoietic stem cell transplantation is widely accepted as effective therapy for patients with relapsed aggressive B-cell non-Hodgkin's lymphoma, and to a lesser extent, for indolent and mantle cell lymphoma, resulting in prolonged disease-free survival. Despite these advances, disease recurrence remains a problem and a major clinical challenge. Allogeneic transplantation has also...

Chronic pancreatitis is a challenging disease; the constellation of chronic abdominal pain and metabolic derangements present unique difficulties to the treating physician. Initial treatment revolves around lifestyle modification, pain control, and management of exocrine insufficiency. In refractory cases, total pancreatectomy with islet cell auto transplantation (TP-IAT) is an option for patie...

Aortoarteritis (Takayasu's Disease) is an inflammatory involvement of Aorta, Pulmonary artery and their large branches and is associated with high perioperative morbidity and mortality. Administration of safe anesthesia to these high risk patients is a challenge and requires knowledge of disease pathophysiology, associated end organ dysfunction, monitoring requirements, potential complications ...

Searching The searches were conducted by two independent reviewers in two different medical literature systems (MEDLINE and TOXLINE) from January 1979 to August 1996. The following keywords were used in different combinations: 'cyclosporine', 'adverse effects', 'nephrotoxicity', 'auto-immune diseases', 'uveitis', 'psoriasis', 'rheumatoid arthritis' and 'inflammatory bowel disease'. Additional p...

Splenosis is a condition in which ectopic spleen tissue may be found in the peritoneal cavity or in other unusual locations due to heterotopic auto-transplantation and implantation of splenic tissue after splenic trauma or splenectomy. It is a benign condition that is often misdiagnosed as a tumor; therefore, knowledge of this condition is important when evaluating patients with a history of sp...

Renal artery aneurysm (RAA) is an unusual vascular disease. Few vascular surgeons have extensive experience with clinical management of RAA.Considerable confusion persists concerning its incidence, cause, and clinical importance. Due to lack of controlled clinical data, controversy also persists regarding the indication for treatment of asymptomatic RAA.We report the case of 46-year-old gentlem...