Aim. To find out the changing trends in indications for use of laparoscopy for diagnostic or operative procedures in gynaecology. Methods. This was a clinical audit of 417 women who underwent laparoscopic procedures over a period of 8 years from January 2005 to December 2012 in the Department of Obstetrics and Gynaecology at a tertiary care centre in Delhi. Results. A total of 417 diagnostic an...

Nuage, a well conserved perinuclear organelle found in germline cells, is thought to mediate the repression of retroelements in Drosophila melanogaster by regulating the production of Piwiinteracting RNAs (piRNAs). Here, we present evidence that the nuage/piRNA pathway components can be found in cytoplasmic foci that also contain retroelement transcripts, anti-sense piRNAs and proteins involved...

Endometrial polyps and submucosal fibroids are common causes of abnormal uterine bleeding (AUB) and less commonly infertility. The prevalence of such intrauterine lesions increases with age during the reproductive years, and usually decreases after menopause. The first-line imaging examination in the diagnosis of endometrial polyps as well as submucosal fibroidsis ultrasound, but its accuracy i...

In Drosophila melanogaster the reciprocal "Ping-Pong" cycle of PIWI-interacting RNA (piRNA)-directed RNA cleavage catalyzed by the endonuclease (or "Slicer") activities of the PIWI proteins Aubergine (Aub) and Argonaute3 (AGO3) has been proposed to expand the secondary piRNA population. However, the role of AGO3/Aub Slicer activity in piRNA amplification remains to be explored. We show that AGO...

INTRODUCTION AND OBJECTIVES The American University of Beirut Faculty of Medicine (AUB-FM) strategy is to develop faculty members (fm) skills by sponsoring local and international scientific activities has been in place for over three decades, and remains dependent on individuals' efforts. In 2011-2012, Faculty Development Program (FDP) was introduced to develop faculty leadership, business ski...

Nuage, a well-conserved perinuclear organelle found in germline cells, is thought to mediate retroelement repression in Drosophila melanogaster by regulating the production of Piwi-interacting RNAs (piRNAs). In this study, we present evidence that the nuage-piRNA pathway components can be found in cytoplasmic foci that also contain retroelement transcripts, antisense piRNAs, and proteins involv...

Transposable elements (TEs) are silenced in germ cells by a mechanism in which PIWI proteins generate and use PIWI-interacting ribonucleic acid (piRNA) to repress expression of TE genes. piRNA biogenesis occurs by an amplification cycle in microscopic organelles called nuage granules, which are localized to the outer face of the nuclear envelope. One cofactor required for amplification is the h...

: Females over 20 years of age come frequently to gynecological clinics, with the complaint Abnormal Uterine Bleeding (AUB). It has a direct impact on physical and mental health females. This research aims detect frequency different uterine causes AUB determine relationship between histopathological lesions associated their groups presentation. Endometrial biopsies / hysterectomy specimens were...

The aim of the research was to evaluate effectiveness optimized treatment in correction hormonal disorders women with abnormal uterine bleeding (AUB) and chronic psycho-emotional stress.
 Materials methods. 100 reproductive age AUB stress were examined. I group included 50 patients who received complex treatment, II persons standard treatment. control 30 healthy without stress. approach pr...