Hu antigen C (HuC) has three RNA-binding domains (RBDs). The N-terminal two, RBD1 and RBD2, are linked in tandem and bind to the AU-rich elements (AREs) in the 3'-untranslated region of particular mRNAs. The solution structures of HuC RBD1 and RBD2 were determined by NMR methods. The HuC RBD1 and RBD2 structures are quite similar to those of Sxl RBD1 and RBD2, respectively. The individual RBDs ...

We consider truncations of nonlinearities of semilinear elliptic problems by H 1 , not necessarily bounded, sub and super solutions. We prove that their associated energy functionals are of class C 1 and satisfy the Palais{Smale condition. We apply this result to prove existence of innnitely many solutions of a supercritical elliptic problem involving concave and convex nonlinearities. Troncatu...

Broadband charge-coupled device photomet ry of Comet p/Halley at heliocentric d is tances R = 5.9 A U (1984 October) and R = 5.1 A U (1985 January) is presented. The mean brightness at R = 5.1 A U is greater than expected from an asteroidal br ightness model fitted to earlier photometry . It is likely that this br ightness increase is due to the release of dus t grains from the nucleus beginnin...

As the amount of sequencing efforts and genomic data volume continue to increase at an accelerated rate, phylogenetic analysis provides an evolutionary context for understanding and interpreting this growing set of complex data. We introduce a novel quartet based method for inferring molecular based phylogeny called hypercleaning* (HC). The HC method is based on the hypercleaning (HC) technique...

The dynamics of the low-lying excited states of vanadyl octaethylporphyrin (OEPVO) in frozen solution is investigated by transient electron paramagnetic resonance (TREPR). The observation of spin-polarized TREPR spectra from the lowest excited trip-quartet state of OEPVO, reported in the preceding paper, opens a new avenue for investigation of the excited states of such molecules. Here, a model...

The dinuclear title mol-ecule, [Au(2)Fe(C(10)H(11)N(2)O(3)S)(2)(C(17)H(14)P)(2)]·2CHCl(3), has crystallographic twofold symmetry with the Fe atom (bonded to two η(5)-cyclo-penta-dienyl rings) situated on the rotation axis. The Au atom exists within a linear geometry defined by an S,P-donor set with a deviation from linearity [S-Au-P = 176.86 (6)°] due to the close approach of the thio-carbamate...

Evolutionary (Phylogenetic) trees are constructs of the biological and medical sciences, their purpose is to establish the relationship between a set of species (phyla). Often it is the case that the true evolutionary tree is unknown and one can only try to estimate it. Reconstruction methods are manifold and the resulting evolutionary trees are not guaranteed to be correct. In order to establi...

The exchange and inelastic state-to-state cross sections for the OH(+) + H collisions are computed from wave packet calculations using the doublet and quartet ground electronic potential energy surface (PES) correlating to the open shell reactants, for collision energies in the range of 1 meV to 0.7 eV. The doublet PES presents a deep insertion well, of ≈6 eV, but the exchange reaction has a ra...

The theory of anti-selfdual (ASD) Lagrangians developed in [8] allows a variational resolution for equations of the form Λu+Au+∂φ(u)+f = 0 where φ is a convex lower-semi-continuous function on a reflexive Banach space X, f ∈ X∗, A : D(A) ⊂ X → X∗ is a positive linear operator and where Λ : D(Λ) ⊂ X → X∗ is a non-linear operator that satisfies suitable continuity and anti-symmetry properties. AS...

We consider, in a Hilbert space H, the convolution integro-differential equation u′′(t)−h∗Au(t) = f(t), 0 ≤ t ≤ T , h∗v(t) = ∫ t 0 h(t−s)v(s) ds, where A is a linear closed densely defined (possibly selfadjoint and/or positive definite) operator in H. Under suitable assumptions on the data we solve the inverse problem consisting of finding the kernel h from the extra data (measured data) of the...