OBJECTIVE To examine whether transcatheter closure of secundum atrial septal defect (ASD) with the Amplatzer septal occluder leads to more myocardial injury in children than in adults. DESIGN In a prospective study with children and adults cardiac troponin I (cTnI) serum concentrations were determined by immunoassay (AxSYM, Abbott Laboratories) before, during, and up to 20 months after surgic...

(A) Before the procedure, large residual ventricular septal shunts could be seen between the occluder and the peak of apex (Online Video 1). (B) After the procedure, the shunts decreased significantly (Online Video 2). LV 1⁄4 left ventricle; RV 1⁄4 right ventricle. A 58-year-old man with exertional dyspnea (New York Heart Association class II) was admitted to our hospital. He suffered from acut...

We carried out transcatheter procedures to close postinfarction ventricular septal defects (PIVSDs) in 19 patients: two had recanalization after surgical closure, and 17 had a primary PIVSD. In three of the latter patients, who had acute PIVSDs, the procedure was carried out in the first 3 weeks after infarction; in the 13 patients with subacute PIVSD, it was carried out 3.5-12 weeks after infa...

We report the management of a patient with secundum atrial septal defect (ASD) and severe pulmonary hypertension. A 65-year-old male with recently diagnosed atrial septal defect was referred to our centre for decompensated right heart failure with rest and exercise induced dispnea and severe pulmonary hypertension. Right heart catheterization confirmed a mean pulmonary pressure of about 55 mmHg...

Transcatheter device closure was performed under general anesthesia in all the patients. The interventional treatment modality was approved by the ethics committee of our hospital, and informed consent was obtained before the procedure. Femoral artery and vein was routinely punctured. Left ventricular angiography was performed at 60° left anterior oblique and 20° cranial tilt position. The entr...

BACKGROUND Despite several reports regarding the use of the Occlutech Figulla® Flex septal occluder (OFFSO) in adults, there are few reports on its use in children. We sought to study the result of the transcatheter closure of atrial septal defect (ASD) using the OFFSO in children ≤12 years. METHODS We enrolled 45 consecutive patients, ranging from 2.5 to 12 years of age, in two large pediatr...

background: there is some evidence indicating improvement in myocardial performance after atrial septal defect closure, either device closure or surgical, but ventricular dyssynchrony has not been evaluated before and after surgical closure. the aim of this study was to evaluate ventricular mechanical dyssynchrony in patients with atrial septal defect before and after surgical closure. methods:...