Objective. Thyrotoxic periodic paralysis (TPP) is a potentially life-threatening complication of Graves' disease (GD). The present study compared the long-term efficacy of antithyroid drugs (ATD), radioactive iodine (RAI), and surgery in GD/TPP. Methods. Sixteen patients with GD/TPP were followed over a 14-year period. ATD was generally prescribed upfront for 12-18 months before RAI or surgery ...

Adolescents with Asperger's syndrome (AS), often have handwriting difficulties that affect their academic performance. The purpose of this descriptive multiple-case mixed-method study was to highlight how adolescents with AS experience writing in the school setting when writing by hand and when using a computerized Assistive Technology Device (ATD), for writing. A qualitative content analysis a...

Studies have long reported that aging is associated with declines in several functions modulated by the prefrontal cortex, including executive functions like working memory, set shifting, and inhibitory control. The neurochemical basis to this is poorly understood, but may include the serotonergic system. We investigated the modulatory effect of serotonin using acute tryptophan depletion (ATD) ...

Based on a sample of 539 angel investors, we empirically test the impact of new ventures’ resource acquisition/allocation strategies in different development stages on angels’ abnormal returns and their extremeness. Our findings suggest that at earlier stages, ventures whose entrepreneurs focus more on securing new resources tend to not only give angel investors lower abnormal returns, but also...

patients with turner’s syndrome (ts) are at an increased risk of developing autoimmune thyroid disease (atd). the aim of this study was to determine the frequency of anti-thyroid peroxidase (anti-tpo) antibodies and atd in children and adolescent girls with ts. it also assessed the influence of karyotype on the development of thyroid disease. sixty eight patients with ts were compared with 68 a...

A abordagem metodológica com histórias de vida tem sido utilizada na pesquisa educacional. Este estudo investiga como a Análise Textual Discursiva (ATD), desenvolvida por Morais e Galiazzi (2016), corrobora compreensão interpretação das dos sujeitos. Fez-se necessário caracterizar as etapas do ciclo análise da ATD, exemplificando-as dados mestrado (AUTOR, 2018). Direciona-se pela qualitativa. C...

This paper develops a theory of how angel and venture capital markets interact. Entrepreneurs first receive angel then venture capital funding. The two investor types are ‘friends’ in that they rely upon each other's investments. However, they are also ‘foes,’ because at the later stage the venture capitalists no longer need the angels. Using a costly search model we derive the equilibrium deal...

Ionotropic glutamate receptors are functionally diverse but have a common architecture, including the 400-residue amino-terminal domain (ATD). We report a 1.8-A resolution crystal structure of human GluR2-ATD. This dimeric structure provides a mechanism for how the ATDs can drive receptor assembly and subtype-restricted composition. Lattice contacts in a 4.1-A resolution crystal form reveal a t...

Machine Learning (ML) techniques now are ubiquitous tools to extract structural information from data collections. With the increasing volume of data, large-scale ML applications require an efficient implementation to accelerate the performance. Existing systems parallelize algorithms through either data parallelism or model parallelism. But data parallelism cannot obtain good statistical effic...