Existing bidirectional model transformation (BX) languages are mainly state-based: model alignment is hidden inside update propagating procedures, and model deltas are implicit. Weaving alignment with update propagation complicates the latter and makes it less predictable and less manageable. We propose to separate concerns and consider two distinct operations: delta discovery (alignment) and d...

Asymmetric development of plant lateral organs is initiated by a partitioning of organ primordia into distinct domains along their adaxial/abaxial axis. Two primary determinants of abaxial cell fate are members of the KANADI and YABBY gene families. Progressive loss of KANADI activity in loss-of-function mutants results in progressive transformation of abaxial cell types into adaxial ones and a...

Some models have been proposed to analyze one-mode three-way data [e.g. De Rooij and Gower (J Classification 20:181–220, 2003), De Rooij and Heiser (Br J Math Stat Psychol 53:99–119, 2000)]. These models usually assume triadic symmetric relationships. Therefore, it is general to transform asymmetric data into symmetric proximity data when one-mode three-way asymmetric proximity data are analyze...

In this paper, we present a novel robust method for point matching under noise, deformation, occlusion and outliers. We introduce a new probability model to represent point sets, namely asymmetric Gaussian (AG), which can capture spatially asymmetric distributions. Firstly, we use a mixture of AGs to represent the point set. Secondly, we use L2-minimizing estimate (L2E), a robust estimator to e...

Evaluation of forecast optimality in economics and finance has almost exclusively been conducted under the assumption of mean squared error loss. Under this loss function optimal forecasts should be unbiased and forecast errors serially uncorrelated at the single period horizon with increasing variance as the forecast horizon grows. Using analytical results we show that standard properties of o...

In this article, I discuss the so-called implicational and-construction and show how it can be derived under Minimalist assumptions. e major challenge is to nd a way to account for the subordinate and the coordinate properties of this construction at the same time. e crucial idea behind the analysis is that the asymmetric syntax of coordination enables the transformation of a subordinate struc...

We provide a mathematical analysis for the appearance of motor effects, i.e., the concentration (as Dirac masses) at one side of the domain, for the solution of a Fokker-Planck system with two components, one with an asymmetric potential and diffusion and one with pure diffusion. The system has been proposed as a model for motor proteins moving along molecular filaments. Its components describe...

Echinoderms are unique in being pentaradiate, having diverged from the ancestral bilaterian body plan more radically than any other animal phylum. This transformation arises during ontogeny, as echinoderm larvae are initially bilateral, then pass through an asymmetric phase, before giving rise to the pentaradiate adult. Many fossil echinoderms are radial and a few are asymmetric, but until now ...

A concise asymmetric (>99:1 e.r.) total synthesis of (+)-anti- and (-)-syn-mefloquine hydrochloride from a common intermediate is described. The key asymmetric transformation is a Sharpless dihydroxylation of an olefin that is accessed in three steps from commercially available materials. The Sharpless-derived diol is converted into either a trans or cis epoxide, and these are subsequently conv...