This study evaluated acute and sub-chronic toxicities in rodents and microbial purity of a polyherbal preparation, Leon Bitters, prepared with Gongronema latifolia (climbing stem), Cocos nucifera (coconut) roots and Parinari curatellifolia seeds. Microbial purity was evaluated on some bacterial and fungal organisms using appropriate diagnostic media. Toxicity of the polyherbal preparation was e...

BACKGROUND Alpha-Glutathione S-transferase (α-GST) is a liver enzyme which showed properties making it useful in assessment of liver cell damage. A number of studies demonstrated its early elevation in different hepatic insults, but its pattern in HCV was controversial. Consequently, we planned this work to study the significance of Serum Alpha-Glutathione S-Transferase (α-GST) assessment in he...

AIM To determine the effects of high osmolarity contrast media (HOCM) and iso-osmolar contrast media (CM) application, with or without pressure, on hepato-pancreato-biliary (HPB) system. METHODS Sixty rats were divided into six equal groups as follows: Group 1: (0.9% NaCl, control), Group 2: (diatrizoate meglumine Na, ionic HOCM, Urographin), Group 3: (iodixanol, iso-osmolar non-ionic CM, Vis...

BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic hepatitis, which can lead to cirrhosis and hepatocellular carcinoma. OBJECTIVES The aim of the study was to evaluate the correlation between serum adipocytokines and the histologic findings of the liver in patients with non-alcoholic fatty liver disease (NAFLD). PATIENTS AND METHODS This case-control study was...

hisH encodes imidazole acetol phosphate (IAP) aminotransferase in Zymomonas mobilis and is located immediately upstream of tyrC, a gene which codes for cyclohexadienyl dehydrogenase. A plasmid containing hisH was able to complement an Escherichia coli histidine auxotroph which lacked the homologous aminotransferase. DNA sequencing of hisH revealed an open reading frame of 1,110 bp, encoding a p...

The kinetics of changes in the tissue content of citric acid cycle intermediates and free amino acids have been investigated in isolated perfused hearts during the transition from substrate-free perfusion to perfusion with medium containing 5 mM glucose and 5 s 10m3 units of insulin per ml. Glycolytic flux increased within 1 min to about 300 pmoles of glucose equivalents per g (dry weight) per ...

The kinetics of changes in the tissue content of citric acid cycle intermediates and free amino acids have been investigated in isolated perfused hearts during the transition from substrate-free perfusion to perfusion with medium containing 5 mM glucose and 5 s 10m3 units of insulin per ml. Glycolytic flux increased within 1 min to about 300 pmoles of glucose equivalents per g (dry weight) per ...