An acetone powder of cat brain catalyzed the synthesis of two radioactive products when incubated with L-aspartate-14C and acetyl coenzyme A. The products were identified as Nacetyl-aspartic acid and citric acid. A water extract of the powder contained the system that produced citrate-14C, while the residue contained the aspartate N-acetyltransferase activity. The soluble system rather than the...

Direct intracerebral administration of N-methyl-D-aspartate typically produces focal brain injury. (+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-immi ne maleate (MK-801), a non-competitive N-methyl-D-aspartate antagonist, can protect against N-methyl-D-aspartate-mediated brain injury when administered shortly before or after an intracerebral injection of N-methyl-D-aspartate. Howev...

Background. Oxidative stress is associated with infertility. This study was conducted to determine the effects of glutamate and aspartate on serum antioxidative enzymes, sex hormones, and genital inflammation in boars suffering from oxidative stress. Methods. Boars were randomly divided into 4 groups: the nonchallenged control (CON) and H2O2-challenged control (BD) groups were fed a basal diet ...

A unique nicotinic acid degradation was devised which permitted the isolation of each individual carbon atom of the pyridine ring. Aspartate-3J4C and malate-3J4C were administered to Nicofzi~na rustica tobacco plants for 4 hours and found to be incorporated almost exclusively into carbons 2 and 3 of the pyridine ring of nicotine. When aspartate-3-l% was fed, 57% of the tracer resided at carbon ...