background new research proposes the pluripotency of spermatogonial cells obtained from testis. these spermatogonia-derived stem cells are called embryonic stem-like cells that express embryonic stem cell markers and differentiate to the three germ layers. objectives the aim of the present study was to generate embryonic stem-like cells from neonatal mouse testis. materials and methods the test...

  SUMMARY With the aim of surgical epidemiology nature of undescended testis, we examined 8034 school age boys in the city of Tehran. We invatted affected persons to Loghman-e-Hakim Medical Center for repeated examination and further diagnostic in­vestigations, results are: Among 8034 persons 82 had undescended testis, it means 1 .02 % , 56 % are in the right, and 33%  in the left, 11 % are...

OBJECTIVE To determine the role of ascending urethrogram in decision making for patients with suspected urethral strictures. METHODS Medical Records were reviewed of male patients presenting with lower urinary tract symptoms who were subjected to ascending urethrogram and selected cases for cystourethroscopy from January 2001 to December 2002. Cystourethroscopy was performed on those patients...

THE undescended testis is more susceptible to trauma (Gross and Jewett 1956) and to malignant change (Collins and Pugh, 1964; Altman and Malament, 1967) than the normally placed testis. It has been shown that degeneration in an ectopic testis begins at about the age of 5 years (Scorer 1967; Cohn 1967). It is therefore generally accepted that orchidopexy should be carried out at around the age o...

BACKGROUND Testicular torsion associated with undescended testis is uncommon but requires immediate treatment. Ultrasound Doppler is recognized as the preferred imaging modality for testicular torsion due to its high specificity, sensitivity and availability. OBJECTIVES To determine the accuracy of ultrasound Doppler in diagnosis of torsion of undescended testis. METHODS We describe three p...

OBJECTIVE To investigate the effects of continued hypoxia on postnatal development of the rat testis. DESIGN Wistar rats were exposed to simulated hypoxia from birth to postnatal day (PND) 45. Testosterone (T) in the plasma and the testis was measured in rats at PND 3, 7, 14, 21, 28, 35 and 45 respectively. Testis histology and cellular ultrastructure were studied. RESULTS a) Hypoxia induce...

BACKGROUND Nuclear protein in testis carcinoma is a rare and very aggressive undifferentiated cancer which characteristically arises in the midline of the head, neck, and mediastinum. CASE PRESENTATION We describe the case of a 46-year-old white woman admitted for superior vena cava syndrome revealing a mediastinal tumor. Pathological examination of specimens obtained by mediastinoscopy revea...

We have developed a new strategy for differential screening of genes that are expressed in two or more tissues, and have used it to identify genes that are preferentially expressed in both testis and ovary. In this approach, testis-specific cDNAs were first generated using the suppression subtractive hybridization technique, cloned and arrayed in microplates. The inserts from the subtracted tes...

In many taxa, the left and right testes often differ in size. The compensation hypothesis states that one testis of the pair serves as a 'back-up' for any reduced function in the other and provides a mechanism to explain intraspecific variation in degree and direction of gonad asymmetry. Although testis asymmetry is common in birds, evidence for natural testis compensation is unknown. Using a n...

A gene, presumably involved in spermatogenesis, was identified and characterized by using cDNA microarray. Hybridization intensity was 2.13 fold higher in adult testis than that in fetal testis. The full length of this gene was 4288 bp and it encoded a 578 amino acid protein. Conserved structure and amino acid sequence analysis revealed that the protein contained 1 Thif-domain, 2 UBACT-domains,...