During the inflammatory response at least 2 transcription factors, NF-kappaB and AP-1, are involved in the altered profile of gene expression. We used human hepatoma (HepG2) and human umbilical vein endothelial cells (HUVEC) as a model system: NF-kappaB and AP-1 were activated by the proinflammatory cytokine IL-1 in the absence or presence of 21 selected plant extracts and the effect was evalua...

calcium response also blocked the induction of LTP. quately explain the supralinearity of the calcium signal issue, 673–685. possibility was suggested by Schiller et al. (1998) on the press. basis of experiments in which they photolysed caged glutamate to produce a controlled level of postsynaptic activation, while simultaneously imaging the resulting calcium transient in dendritic spines. This...

35 Unbiased Equation-Error Adaptive IIR Filtering Based on Moni Normalization Hyoung-Nam Kim, Student Member, IEEE, and Woo-Jin Song, Member, IEEE Abstra t| We present a novel way to remove the bias in equation-error based adaptive in nite impulse response (IIR) ltering by on eiving a s heme alled moni normalization. It is found that normalizing all the oeÆ ients of the denominator lter by the ...

The zebrafish model organism was applied first in a metabolic study of icariin, baohuoside I, epimedin A and epimedin C, which are flavonoids in Herba Epimedii. Metabolites of these compounds in zebrafish after exposure for 24 h were identified by HPLC-ESI-MS, whereby the separation was performed with a Zorbax C-18 column using a gradient elution of 0.05% formic acid acetonitrile-0.05% formic a...

Based on re ent experimental data, we have developed a ondu tan e-based omputational network model of the subthalami nu leus and the external segment of the globus pallidus in the indire t pathway of the basal ganglia. Computer simulations and analysis of this model illuminate the roles of the network's oupling ar hite ture, and asso iated synapti ondu tan es, in modulating the a tivity pattern...

Melandrii Herba (MH) is a traditional Asian medicinal herb used to treat breast cancer, anuria, and diseases of lactation. However, its biological properties and molecular mechanisms have not been fully elucidated. The purpose of this study was to investigate the anti-inflammatory activity and underlying molecular mechanism of MH ethanol extract (MHE) on the lipopolysaccharide (LPS)-mediated in...

165 Pain management is a very im portant aspect of nursing care of the pediatric patient. Ac cording to the Inter national Association for the Study of Pain (IASP), Special Interest Group on Pain in Childhood (2005), pain relief is a human right. Since 2001, pain management standards require that pro viders be educated in the assessment and management of pain, and that they recognize the right ...

Italy comprises a high proportion of people who never exercised. Low physical activity levels in adolescents is a risk factor for several disorders. The aim of this cohort epidemiological study was to compare physical fitness profiles between boys and girls with regard to age and gender and to identify health and fitness-related markers that contribute to the make-up of Southern Italian teenage...

The genus Artemisia (Asteraceae, Anthemideae, Artemisiinae) is a large genus, one of the largest genera in its family. It is comprised of about 500 taxa at the specific or subspecific level, distributed in 5 sections or subgenera. Most species are perennial and many are landscape dominants of arid or semiarid regions. Artemisia is widely distributed in the Northern Hemisphere but poorly represe...