Allergic rhinitis (AR) is one of the most common allergic diseases, affecting 20% of the adult population and up to 40% of children (Salib et al., 2003). It is associated with decreased learning, performance and productivity at work and school, as well as a reduced quality of life. The detrimental effects of AR on quality of life (QOL) include fatigue, irritability, memory deficits, excessive d...

BACKGROUND AND OBJECTIVE In order to characterize the β-adrenoceptor (AR) subtypes involved in agonist-stimulated relaxation of murine urinary bladder we studied the effects of (-)-isoprenaline and CL 316,243 on tonic contraction and spontaneous contractions in detrusor strips of wild-type (WT) and β2-AR knockout (β2-AR KO) mice. MATERIALS AND METHODS Urinary bladders were isolated from male ...

Allergic rhinitis (AR) is a widespread medical condition affecting up to 40% of the general population. Type 2 inflammation determines typical nasal symptoms. In addition, gut and respiratory dysbiosis are present in AR patients. Probiotics have several beneficial effects on immunity, inflammatory pathways, anti-infective properties. Namely, probiotic supplementation could restore immune respon...

BackgroundAir pollutants are suspected to affect pathological conditions of allergic rhinitis (AR).ObjectivesAfter detecting Pb (375 ?g/kg) in Japanese cedar pollen, the effects intranasal exposure on symptoms AR were investigated.MethodsPollen counts, subjective symptoms, and levels nasal epithelial lining fluid (ELF) investigated 44 patients with pollinosis 57 controls from preseason season. ...

We concerned on the role of secondary electrons in low pressure rf glow discharge. The Particle in Cell/Monte Carlo computer simulations (PIC/MC) was applied to simulate the discharge. The influence of secondary electron emission yield (SEY) on the plasma density was studied. Furthermore the relative density and the electron energy probability function of secondary particles, i.e., secondary el...

40 Ar/ 39 Ar analyses were made on maruyamaite (potassium-dominant tourmaline) from tourmaline-quartz-feldspar rocks discovered within the Kumdy-Kol microdiamond deposit (Kokchetav massif, North Kazakhstan). Turmaline yielded well-defined plateau age spectra whose values coincide error - ages of 502.3±8.0, 502.2±8.0, 506.0±8.0 Ma. These are much younger than 530±2 Ma determined for high-pressur...