The purpose of this study was to determine the temporal appearance of T. gondii in aqueous humor of cats orally inoculated with T. gondii using polymerase chain reaction (PCR) for the detection of the B1 gene. Serum and aqueous humor were collected from five SPF cats prior to oral inoculation with T. gondii and days 7, 14, 21, 28, 42, 84, 140, 147, 154, 161, 168, and 182 after inoculation. Cats...

BACKGROUND To measure ascorbic acid concentration in aqueous humor of patients with cataract after oral or intravenous vitamin C supplementation. METHODS Forty-two eyes of 42 patients with senile cataract who underwent uncomplicated cataract surgery were enrolled. Patients (n = 14 each) were administered oral vitamin C (2 g), intravenous vitamin C (20 g) or no treatment (control group) on the...

Albumin labelled with '•"/ and I was used to determine at the same time and. in both eyes the rates of conventional and uveoscleral bulk drainage of aqueous humor in cynomolgus monkeys under pentobarbital anesthesia. With 10'* M per liter of pilocarpine in the anterior chamber, the rate of conventional bulk drainage of aqueous humor was 0.98 ± 0.19 nl per minute as compared with 0.56 ± 0.12 fil...

Citation: Bauer D, Kasper M, Walscheid K, Koch JM, Müther PS, Kirchhof B, Heiligenhaus A and Heinz C (2018) Multiplex Cytokine Analysis of Aqueous Humor in Juvenile Idiopathic Arthritis-Associated Anterior Uveitis With or Without Secondary Glaucoma. Front. Immunol. 9:708. doi: 10.3389/fimmu.2018.00708 Multiplex cytokine analysis of aqueous humor in Juvenile idiopathic arthritis-associated anter...

Trabeculectomy is the most commonly used surgical procedure for managing medically uncontrolled glaucoma. It reduces intraocular pressure (IOP) by creating an artificial drainage pathway of the aqueous humor from the anterior chamber to the subconjunctival space, forming a filtering bleb. Aqueous humor in the subconjunctival space may then exit by multiple pathways including transconjunctival f...

A double-blind, randomized, placebo-controlled study of the effect of 0.5% topical thymoxamine hydrochloride an alpha-adrenergic antagonist, on the rate of aqueous humor formation in the eyes of 25 normal human subjects was performed with fluorophotometry. The effect of thymoxamine on intraocular pressure and anterior chamber volume was also studied. four of the 25 subjects were used to study t...

Richard F. Figure 1 shows a human eye without its aqueous circulation. The cornea is thickened, the anterior chamber is absent, the iris is partly atrophic, and the lens is cataractous. The picture serves as a reminder of the dependency of the health of the eye on the continuous supply of aqueous humor that circulates through its chambers. It is surprising that it was not known until recently t...

PURPOSE To compare the changes in the levels of 27 aqueous humor cytokines between nondiabetic controls and patients with type 2 diabetes and to ascertain the association of these cytokines with diabetic retinopathy (DR). METHODS Undiluted aqueous humor samples were obtained from 102 nondiabetic patients (102 eyes) and 136 consecutive diabetic patients (136 eyes) who were divided into nine gr...

Antidromic stimulation of the trigeminal nerve produces an irritative response in the rabbit eye characterized by ipsilateral miosis, hyperemia, elevated intraocular pressure, and a disruption of the blood-aqueous barrier. The latter is a bilateral effect. The mediator or mediators involved in this response of the eye are unknown. Increased ATP levels in aqueous humor could be found after trige...

Following application of 20 mul of 2 N sodium hydroxide to the rabbit cornea, the prostaglandin-like activity in the aqueous humor increased from undetectable levels to around 30 ng, per milliliter, a level which was sustained for up to 24 hours. This increase correlated with the previously reported sustained elevation of intraocular pressure following a 20 mul alkali burn. Pretreatment with as...