Analysis of the chemokine analogs synthesised on a terpolymer-polystyrene, N-vinylpyrrolidone, 1,6-hexanediol diacrylate crosslinked resin (PS-NVP-HDDA) showed it can be used good solid support for chemical synthesis polypeptides. The polymer with swelling character and resistance was by radical aqueous suspension polymerisation technique. HPLC analysis crude peptides PS-NVP-HDDA that is better...

DNA-templated organic synthesis (DTS) enables new modes of controlling chemical reactivity and allows evolutionary principles to be applied to the discovery of synthetic small molecules, synthetic polymers, and new chemical reactions. The structures that can be accessed in a DNA-templated format thus far have been limited to those that can be generated in aqueous solvents. Here we report effici...

Enzymes are the most efficient catalysts known for working in an aqueous environment near room temperature. The folding of individual polymer chains to functional single-chain nanoparticles (SCNPs) offers many opportunities for the development of artificial enzyme-mimic catalysts showing both high catalytic activity and specificity. In this review, we highlight recent results obtained in the us...

The synthetic hydroxyapatite is a very useful material for numerous applications in medicine as a biomaterial. One of the most economic manufacturing process is the precipitation route. In the present work, synthetic hydroxyapatite was prepared using the precipitation route, starting with aqueous solutions of calcium nitrate (Ca(NO3).4H2O ) and ammonium phosphate (H2(PO4)NH4). The effects of ph...

Enzymes are the most efficient catalysts known working in an aqueous environment near 12 room temperature. The folding of individual polymer chains to functional single-chain nanoparticles 13 (SCNPs) offers many opportunities for the development of artificial enzyme-mimic catalysts 14 showing both high catalytic activity and specificity. In this review, we highlight recent results 15 obtained i...

The search for drugs with cytostatic activity and with better pharmacokinetic features led to the synthesis of Navelbine (5'-noranhydrovinblastine) which is a structural modification of antitumour Vinca alkaloids. The new drug Navelbine has high liposolubility, a lower toxicity and increased antitumour activity. The electrochemical oxidation of Navelbine was studied over a wide pH range (1.2-12...

This review paper on amorphous calcium phosphates (ACPs) provides an update on several aspects of these compounds which have led to many studies and some controversy since the 1970s, particularly because of the lack of irrefutable proof of the occurrence of an ACP phase in mineralised tissues of vertebrates. The various synthesis routes of ACPs with different compositions are reported and the t...

Water has emerged as a versatile solvent for organic chemistry in recent years. Water as a solvent is not only inexpensive and environmentally benign, but also gives completely new reactivity. The types of organic reactions in water are broad including pericyclic reactions, reactions of carbanion equivalent, reactions of carbocation equivalent, reactions of radicals and carbenes, transition-met...

Aqueous solutions of various types honey as a source reducing sugars – glucose and fructose, were used to accelerate or control activators regeneration by electron transfer atom radical polymerization (ARGET ATRP) in homogeneous heterogeneous environment. The aqueous alcoholic-aqueous solution was applied for the hydrophilic methacrylates i.e. 2-(dimethylamino)ethyl methacrylate (DMAEMA), glyci...