OBJECTIVE To assess whether maternal multiple sclerosis (MS) is associated with adverse pregnancy outcomes by determining the clinical course of disease during pregnancy and postpartum throughout a 10-year-period in a single tertiary center. METHODS We conducted a case-control study that included pregnancies with a definitive diagnosis of MS (n=43), matched with 100 healthy pregnant women wit...

Background: To study the effect of amniotomy on the duration of labour and Apgar Score of babies in laboring multigravidae Methods: In this interventional study, 100 women with uncomplicated term pregnancy and spontaneous onset of labour were divided in two groups. Patients were in active labour with Bishop score 5-6 and intact membranes. Fifty women underwent amniotomy (groupA) while fifty wom...

INTRODUCTION Lateralization of brain functions such as language and manual dominance (hand preferences and fine motor control) are most likely under genetic control. However, this does not preclude the effect of various environmental factors on functional brain lateralization. A strong association of non-right-handedness (left- and mixed-handedness) with various neurodevelopmental conditions (e...

Accurate clinical assessments are essential for providing appropriate patient care. However, clinicians do not necessarily make accurate assessments, either because they are overloaded with other tasks, or because the computation of assessments is ambiguous. We used Brunswik‟s probabilistic functionalism to study how clinicians assessed the clinical state of a mannequin when they viewed recordi...

BACKGROUND The aim of this retrospective study was to explore the relationship between psychotropic medication dosage and birth outcomes. METHODS A total of 136 women were enrolled, who had an active mental disorder, were taking medication to prevent a relapse, or had a history of postpartum depression or psychosis. Medication use was evaluated for the three trimesters and during labor. Based...

OBJECTIVE To examine whether the combination of a low five minute Apgar score and symptoms of neonatal encephalopathy is associated with minor impairments at school age. DESIGN Population based cohort study. SETTING Norway. PARTICIPANTS All 727 children of the cohort were born between 1983 and 1987, had normal birth weights, no congenital malformations, and no major neurological abnormali...

BACKGROUND Asthma is common among children, adolescents, and adults. However, management of asthma often fails to follow evidence-based guidelines. Control assessments have been developed, validated against expert opinion, and disseminated. However, in primary care, assessment of control is only one step in asthma management. To facilitate integration of the evidence-based guidelines into pract...

Please cite this paper as: Berglund S, Pettersson H, Cnattingius S, Grunewald C. How often is a low Apgar score the result of substandard care during labour? BJOG 2010;117:968-978. Objective To increase our knowledge of the occurrence of substandard care during labour. Design A population-based case-control study. Setting Stockholm County. Population Infants born in the period 2004-2006 in Stoc...