Bioactive composite macroporous scaffold containing nanoporosity was prepared by incorporation of nanoporous magnesium silicate (NMS) into poly(butylene succinate) (PBSu) using solvent casting-particulate leaching method. The results showed that the water absorption and in vitro degradability of NMS/PBSu composite (NMPC) scaffold significantly improved compared with magnesium silicate (MS)/PBSu...

Fundamental aspects of biomineralization may be important in order to understand and improve calcification onto the surface of biomaterials. The biomineralization process is mainly followed in vitro by assessing the evolution of the apatite layer that is formed upon immersion of the material in Simulated Body Fluid (SBF). In this work we propose an innovative methodology to monitor apatite depo...

Samples of porous Ti metal were subjected to different acid and heat treatments. Ectopic bone formation on specimens embedded in dog muscle was compared with the surface characteristics of the specimen. Treatment of the specimens by H2SO4/HCl and heating at 600 °C produced micrometer-scale roughness with surface layers composed of rutile phase of titanium dioxide. The acid- and heat-treated spe...

Biporous (macro- and microporous) calcium phosphate gains much attention as a bone substitute material because of its large surface area and that it improves cell penetration. In the present study, we evaluated the feasibility of biporous, low-crystalline apatite based on dissolution of mannitol from self-setting apatite cement (Biopex). Mannitol--known as a biocompatible, easily dissolved mono...

A Biodegradable artificial bone with inter-connective pores was prepared using a self-setting apatite/collagen composite cement as a cell scaffold for bone regenerative medicine, and investigated as to biocompatibility by X-ray computed tomography (CT) after its implantation into rats. Blocks (APN, APC and ACC) of apatite cement, apatite cement with continuous holes, and apatite/collagen compos...

[1] Recent calibration studies have expanded the range of target minerals suitable for cosmogenic He dating to include U and Th‐rich phases such as zircon, apatite, and titanite. These minerals often contain large amounts of radiogenic He that present several analytical challenges for precise and accurate He determinations. In this paper we document the abundance sensitivity and changes in the ...

4 He/ 3 He apatite thermochronometry and the 13 C-18 O carbonate paleothermometry

Gallstones from three hamsters were studied. The only crystalline material present in detectable amounts was apatite.

The mechanism of cartilage calcification has been outlined in recent reviews."' A study of epiphyseal cartilage calcification has clearly established that the first crystals of apatite that are found in the hypertrophic zone are found in matrix vesicles, in the longitudinal septa.' 2 Matrix vesicles are extracellular, membranous particles, about 100 nm in diameter, that are associated with calc...