HEADINGS Tracking. Premalignant lesions. Anus neoplasms. HIV. ABSTRACT Introduction squamous cell carcinoma of the anal canal is a disease that affects the middle-aged adults and accounts for 4% of cancers of the gastrointestinal tract below. In the general population the incidence is 1 in 100,000, and among men who have sex with men the incidence is 35 per 100,000 inhabitants, those with HIV h...

An 8-month-old female thoroughbred foal was presented showing signs of colic. The foal was anxious,exhibiting signs of abdominal pain and distention. The foal had tachycardia (120 beats/min), tachypnea (40breaths/min). Blood samples obtained for haematologic and serum biochemistry analysis that showed a PCVof 30% and a TPP of 70 g/L. The peritoneal fluid analysis revealed a clear fluid with mil...

Introduction: Combination of congenital diaphragmatic hernia (CDH) and anorectal malformation (ARM) is rare. In this report, we describe a combination of imperforate anus and CDH in one of twins who conceived by Assisted Reproductive Technology (ART). Case Report: A female preterm newborn at 27 weeks of gestation was referred to our neonatal intensive care unit due to respiratory distress. S...

PURPOSE Filaggrin proteins are expressed in the skin, oral cavity, oesophagus, and cervical mucose. Loss-of-function mutations in the filaggrin gene (FLG) reduce filaggrin expression and cause an impaired skin barrier function. We hypothesized that FLG mutation carriers would be more susceptible to human papillomavirus (HPV) infection and thus a higher risk of HPV-related cancer and pre-cancer....

OBJECTIVES The aim of this study was to explore the characteristics of digestive organ cancer mortality and the potential years of life lost in Inner Mongolia, and to provide evidence for the prevention of digestive organ cancers. METHODS Using data from the Death Registry System from 2009 to 2012, we classified male and female cancer deaths according to the International Classification of Di...

Although several cases of signet-ring cell carcinoma (SRCC) in the colorectum have been reported [1,2], there have been no reports of SRCC in the anus. The case presented here is the first reported case of primary pure SRCC of the anus. A 49-year-old man presented with anal bleeding. Colon endoscopy revealed a polyp in the anus, and polypectomy was performed The polypectomy specimen showed pure...

background: the gold standard of the management of rectal cancer in the middle and lower parts is low anterior resection with coloanal anastomosis. about 50% of the patients undergoing this procedure might experience some complications because of the low capacity of the neorectum. the aim of this study was to evaluate ileal j-pouch interposition as a neorectum between the anal canal and the rem...

OBJECTIVE The aim of this meta-analysis is to provide recommendations for clinical practice and prevention of postoperative complications, such as circumferential resection margin (CRM) involvement, and compare the amount of intraoperative bleeding, safety, operative time, recovery, outcomes, and clinical significance of robot-assisted and conventional laparoscopic procedures in anus-preserving...

Introduction: Between 1987 and 1994 three randomised phase III trials demonstrated that chemoradiotherapy with Mitomycin C and 5Fluorouracil was superior to radiotherapy alone (ACT1, EORTC) or radiotherapy with 5Fluorouracil (RTOG 87-04 ECOG 1289) for squamous cell carcinoma (SCC) of the anus. We explored the population-based changes in England before, during and after the UK-based ACT1 trial. ...

There is confusion in the minds ofmany clinicians about the exact anatomical features of the individual lesions of anorectal anomalies and therefore about the way in which they should be treated. This arises partly because some, like the covered anus, are visible in the perineum, whereas in others part of the anomaly is visible, for example, in a low vaginal fistula, but the more important part...