A major cause of morbidity and mortality in the context of the antiphospholipid syndrome (APS) is the occurrence of thrombotic events. Besides the pathogenic roles of antiphospholipid antibodies (aPL), other risk factors and medical conditions, which are conditions for traditional risk of an individual without the APS, can coexist in this patient, raising their risk of developing thrombosis. Th...

Antiphospholipid syndrome is a well-defined entity that is characterized by spontaneous abortion, thrombocytopenia, and recurrent arterial and venous thromboses. A partially calcified right atrial thrombus mimicking myxoma with recurrent pulmonary embolism has not been previously reported in a patient who also had systemic lupus erythematosus and secondary antiphospholipid syndrome. Herein, we ...

Primary antiphospholipid syndrome (APS) is a disease producing vascular thrombus with antiphospholipid antibody without association with autoimmune diseases as systemic lupus erythematosus. Retinal vein occlusion is a rare vascular manifestation in primary APS. We describe 2 cases of primary APS presenting with developing blurred vision. Each had central retinal vein occlusion and high titer of...

A ntiphospholipid syndrome is a multisystem disorder characterized by recurrent thromboses and various neuropsychiatric manifestations. In this study, Tektonidou et al examined the presence of cognitive dysfunction in 60 patients with antiphospholipid syndrome and its association with the clinical, laboratory, and cerebral magnetic resonance imaging characteristics. The authors found that cogni...

L UPUS ANTICOAGULANTS, and “antiphospholipid” autoantibodies in general, are of considerable clinical importance because of their strong association with thrombosis, recurrent fetal loss, and thrombocytopenia, ie, the “antiphospholipid” antibody syndrome.’ This review focuses on recent evidence that “antiphospholipid” autoantibodies are not directed against anionic phospholipids, as has previou...