In the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. The hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. In the control group, the hearts were perfused by normal drug free Krebs-Henseleit (K/H) solution t...

Background: The main target of treatment STEMI is to restore coronary blood flow and maintain myocardial perfusion. Several tools including electrocardiographic angiographic parameters are used assess reperfusion. Fragmented QRS associated with increased adverse cardiovascular events, it was proved bea marker ventricular dysfunction poor prognosis in STEMI. Aim the work : To study relation betw...

OBJECTIVES The clinical significance of ischemia/reperfusion of the lower extremities demands further investigation to enable the development of more effective therapeutic alternatives. This study investigated the changes in the vascular reactivity of the rabbit femoral artery and nitric oxide metabolites under partial ischemia/ reperfusion conditions following cilostazol administration. METH...

BACKGROUND Acidosis during early reperfusion is reported to be beneficial for myocardial stunning. We tested in 31 dogs the hypothesis that staged reperfusion is beneficial to myocardial stunning. METHODS AND RESULTS Contractile dysfunction was observed 3 hours after the onset of reperfusion after 15 minutes of occlusion of the coronary artery. In the staged reperfusion, pH of the coronary ve...

While coronary thrombolytic therapy in clinical practice is well established for acute myocardial infarction, the injury associated with reperfusion ("reperfusion injury") is still under intense investigation regarding its nature and the strategy for its prevention. Reperfusion injury has been defined as cell injury caused by reperfusion itself, in contradistinction to cell injury caused by the...

Introduction. In the structure of modern injuries in wartime and peacetime share gunshot wounds increased significantly. The timeliness applying a tourniquet is one main methods saving lives on battlefield. patterns formation enteral insufficiency syndrome conditions acute blood loss complicated by ischemia-reperfusion limb have not been studied enough. There are no data features violations abs...

The use of hemostatic tourniquet is a proved means primary care. However, systemic disorders, as well ultrastructural, in the area compression can significantly worsen condition injured organism.
 aim. Estimation catalase level rats’ liver on background modifications ischemic-reperfusion syndrome to know severest pathogenic combination for Materials and methods. 260 white adult male rats w...

Not only the prevalence, but also death rate from coronary heart disease, including myocardial infarction, is higher in older people than among young people. A demographic shift towards an aging population will lead to a further increase prevalence of cardiovascular diseases elderly population. Therefore, one urgent aims modern experimental and clinical medicine develop methods aimed at limitin...

background: proanthocyanidin is a potent bioactive antioxidant naturally occurring in grape seed and acts as reactive oxygen species (ros) scavenger. the aim of this study was to investigate the effects of proanthocyanidinin in experimental ovarian torsion injury.   methods : twenty four rats were randomly divided into three groups (n=8). group 1: the laparotomy group, group 2: ovarian torsion ...

objective(s)ischemia-reperfusion injury (iri) is a leading cause of kidney transplantation failure, and ischemic-preconditioning (ipc) is a protective method against the iri. in the present study, the defensive effect of ipc on rats’ kidney was investigated and more importantly the differences between two genders were appraised.materials and methodsthirty two wistar rats were randomly allocated...