In this work we evaluated antidepressant-like effect of E. uniflora leaves EO employing the tail suspension test. The involvement of serotonergic and adrenergic systems was appraised. EO was administered by oral route (p.o.) in mice and the doses of 10 and 50mg/kg exhibited antidepressant-like action in the TST. The effect of EO (10mg/kg) was prevented by the pretreatment of mice with ketanseri...

Origanum vulgar belongs to the plant family of Asteraceae , native to temperate Asia, but naturalized in many countries including scattered parts of North America (11, 12). It is an annual short-day plant. Its stem is erect brownish or violet brown. The aim of this study was to overview its Antioxidant, anticancer, antimicrobial effect. This review article was carried out by searching studies i...

we studied the antioxidant activities of the essential oils of zataria multiflora boiss. (zeo) and bunium persicum (boiss.) b. fedtsch (beo) in mixed form on linseed oil using (dpph•), ­(­abts•+), h2o2 scavenging, and reducing power assays. after calculation of ic50 for zeo and beo separately, interactions of the essential oils were investigated at the form of mixture and the results were given...

We analyzed the protective effect of garlic oil on hepatic and blood lipid peroxidation and the antioxidant status during buccal pouch carcinogenesis induced by 7,12dimethylbenz[a]anthracene (DMBA) in male Syrian hamsters. Enhanced lipid peroxidation in the liver and blood of tumor-bearing animals was accompanied by a significant decrease in antioxidant levels. Topical application of garlic oil...

Objective(s):Paclitaxel is a potent chemotherapy agent with severe side effects, including allergic reactions, cardiovascular problems, complete hair loss, joint and muscle pain, which may limit its use and lower its efficiency. The cardioprotective effect of royal jelly was investigated on paclitaxel-induced damages. Materials and Methods:Adult male Wistar rats were divided into control and te...

The protective effect of black tea extract (BTE) against HgCl2-induced oxidative damage in Wistar rats was investigated. Rats were injected with HgCl2 (5 mg/kg body weight in 0.9% NaCl) to induce oxidative stress. The aqueous BTE (2.5%) was prepared from CTC (curl, tear, crush) grade tea. BTE was fed to control and HgCl2-treated rats by gavage at a dose of 1 ml/(100 g body weight d). Biomarkers...

Hyperlipidemia and many other metabolic diseases are related to oxidative stress. Centella asiatica is a traditional Chinese medicine whose antioxidant effect in vitro has been reported. We are interested in whether it possesses this effect in vivo and hence modulates lipid metabolism. Therefore, experiments were carried out on mice and golden hamsters regarding its antioxidant and hypolipidemi...

Tetramethylpyrazine (TMP) is an active compound isolated from a Chinese herbal prescription that is widely used in traditional Chinese medicine for the treatment of inflammatory and cardiovascular diseases. We have previously reported that TMP acts as a potent antioxidant protecting endothelial cells against high glucose-induced damages. However, the molecular mechanism responsible for the anti...

Anthocyanin is a powerful natural antioxidant. Purple corn husk is rich in anthocyanin. In this paper the antioxidative effect of anthocyanin-rich purple corn husk extract (PCHE) in mayonnaise during storage was studied. The antioxidative effect of the mayonnaise containing PCHE was evaluated by measuring peroxide values, p-anisidine values, total oxidation values, acid values, and iodine value...

In the present work, we have investigated nutritional, phytochemical content and antioxidant activity of ripe fruits of Ziziphus nummularia Burm. f., one of the underutilized plants distributed in drier parts of North Western India. Fruits were quantitatively analyzed for their total phenolic, flavonoid and flavonol content colorimetrically. Nutritional properties including moisture, fats, carb...