نتایج جستجو برای: antimalarial activities

تعداد نتایج: 382933  

Journal: :Archiv der Pharmazie 2015
Rupinder K Gill Ravindra K Rawal Jitender Bariwal

Benzothiazole is a privileged heterocyclic scaffold having a benzene ring fused with a five-membered thiazole ring. This moiety has attracted considerable attention because of its wide range of pharmacological activities such as antitubercular, antimicrobial, antimalarial, anticonvulsant, anthelmintic, analgesic, anti-inflammatory, antidiabetic, antitumor activity, etc. In the last few years, s...

Journal: :Journal of vector borne diseases 2014
Gayan S Bamunuarachchi Wanigasekara D Ratnasooriya Sirimal Premakumara Preethi V Udagama

BACKGROUND & OBJECTIVES Artemisinin isolated from Artemisia annua is the most potent antimalarial against chloroquine resistant Plasmodium falciparum malaria. We previously reported that the ethanolic leaf extract of Artemisia vulgaris, an invasive weed and the only Artemisia species in Sri Lanka, possess both potent and safe antimalarial activity (in terms of antiparasitic properties) in a P. ...

Journal: :Antimicrobial agents and chemotherapy 2005
Robin Das Gupta Tanja Krause-Ihle Bärbel Bergmann Ingrid B Müller Alex R Khomutov Sylke Müller Rolf D Walter Kai Lüersen

The intraerythrocytic development of Plasmodium falciparum correlates with increasing levels of the polyamines putrescine, spermidine, and spermine in the infected red blood cells; and compartmental analyses revealed that the majority is associated with the parasite. Since depletion of cellular polyamines is a promising strategy for inhibition of parasite proliferation, new inhibitors of polyam...

Journal: :iranian journal of health sciences 0
maryam mobini research center of diabetes, mazandran university of medical sciences, sari, iran. ahmad ahmadzadeh-amiri research center of diabetes, mazandran university of medical sciences, sari, iran. soghra khani research center of diabetes, department of midwifery and reproductive health, mazandran university of medical sciences, sari, iran.

background and purpose: occular toxicity is one of the most important complications of hydroxychloroquine. not any type of treatment has so far been found and recommended for this disorder. the purpose of this study was to report some characteristics of patients with hydroxychloroquine induced retinopathy.    materials and methods: from 107 patients with rheumatoid arthritis (ra) and/or systemi...

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