INTRODUCTION The occurrence of multi-antibiotic resistance among enterococci is a prevalent clinical problem worldwide and continues to get serious due to the lack of efficient therapeutic options by the time. In this regards, prokaryotic antimicrobial peptides with bactericidal or bacteriostatic activity which are directed against bacterial strains closely related to producer strains looks one...

purpose: in this study, we have focused on antibacterial effect of newly synthesized thiazole, imidazole and tetrahydropyrimidine derivatives in iran on listeria monocytogenes. materials and methods: for evaluation of antibacterial effect, the disk diffusion method was applied to measure the growth inhibition zone diameter and broth micro dilution was performed to determine the minimum inhibito...

We tested 259 methicillin-resistant Staphylococcus aureus isolates and 2 USA300 ATCC type strains for susceptibility to bacitracin and neomycin contained in over-the-counter antibacterial ointments. Resistance to both bacitracin and neomycin was found only in USA300. The use of over-the counter antimicrobial drugs may select for the USA300 clone.

introduction: thymbra spicata (t. spicata) is a conventional medicinal herb which is commonly used in the folklore medicine system of iran. aim of the study was to assess the antibacterial activity of the essential oil and hudroalcholic extract of the plant t. spicata on some important bacteria. materials & methods: the essential oil and extract of t. spicata were obtained by hydrodistillation ...

background: coagulase negative staphylococci (cons) are one of the most common bacteria found on human skin and on mucous membranes as a component of normal flora. the presence of cons in clinical specimens is frequently associated with an infectious aetiology or contamination. objectives: we aimed to evaluate cons species distribution and susceptibility patterns in specimens obtained from clin...

BACKGROUND Symptomatic and asymptomatic bacteriuria (ASB) is common in pregnant women. Pregnancy enhances the progression from ASB to symptomatic bacteriuria, which if left untreated, could lead to acute pyelonephritis and other adverse outcomes such as prematurity, postpartum, hypertensive disease, anaemia, UTIs and higher foetal mortality rates. AIM To identify the prevalence of ASB, the mo...

SUSCEPTIBILITY TESTS Antibacterial susceptibility testing is not necessary for every case in veterinary medicine because the majority of cases can be treated empirically. But performed properly, antibiotic susceptibility results are helpful to select proper antibacterial therapy for patients with refractory infections, seriously ill animals, or when resistant strains of bacteria are suspected. ...

The incidence of multidrug-resistant bacterial infections is increasing globally and the need to understand the underlying mechanisms is paramount to discover new therapeutics. The efflux pumps of Gram-negative bacteria have a broad substrate range and transport antibiotics out of the bacterium, conferring intrinsic multidrug resistance (MDR). The genomes of pre- and posttherapy MDR clinical is...

Emerging antibiotic resistance in pathogenic bacteria like Mycobacterium sp., poses a threat to human health and therefore calls for the development of novel antibacterial strategies. We have recently discovered that bacterial membrane peptides, such as KdpF, possess anti-virulence properties when overproduced in pathogenic bacterial species. Overproduction of the KdpF peptide in Mycobacterium ...