staphylococcus aureus, as one of the main agentsfor hospital infections,is considered as highly important because they show resistance to a wide range of antibiotics.resistance to selective antibiotics such as vancomycin is a serious problemin the medical community; thus it seems rational to use alternative substances for treating these bacteria.the aim of this study isto investigate the preval...

Introduction and objective: Proteus bacilli are opportunistic members of Enterobacteriaceae and Proteus mirabilis is among the most common causes of community or hospital acquired urinary tract infections (UTI) in many countries. In the present study hemolysin production, salt tolerance and resistance to antibacterial agents in environmental and UTIs samples were compared. Materials and methods...

ORAL PRESENTATIONS Discussion: Cross-resistance to different antibacterial agents including quinolones and nalidixic acid, chloramphenicol, trimethoprim and in some cases b-lactam antibiotics is a common phenomenon in Gram-negative bacteria (Gutmann et al., 1995). In this study adaptive resistance in Salmonella enterica and E. coli O157, O55 and K-12 was readily achieved by passage in sublethal...

Carbapenem resistance due to acquired metallo-beta-lactamases (MBLs) is considered to be more serious than other resistance mechanisms. The aim of this study was to evaluate the antibacterial activity of Zataria multiflora Boiss and Carum copticum plants on IMP-producing P.aeruginosa strains. This experimental study was carried out on hospitalized burn patients during 2011 and 2012. Antibiotics...

Retapamulin is a novel semisynthetic pleuromutilin antibiotic specifically designed for use as a topical agent. The unique mode of action by which retapamulin selectively inhibits bacterial protein synthesis differentiates it from other nonpleuromutilin antibacterial agents that target the ribosome or ribosomal factors, minimizing the potential for target-specific cross-resistance with other an...

Antibacterial/antibiotic drugs have tremendously improved the health of humans and animals since the antibiotic golden age up to date. Currently the emergence of antibiotic/antibacterial resistance due to irrational drug use in medical and veterinary practice, food industries, agriculture and in communities is posing a global health problem. Most of the unused drugs, drug metabolites and residu...

BACKGROUND The challenge of antibiotic resistance and the emergence of new infections have generated considerable interest in the exploration of natural products from plant origins as combination therapy. In this context, crude ethanolic extract (CEE), ethyl acetate fraction (EAF), and methanolic fraction (MF) from Anacardium microcarpum were tested alone or in combination with antibiotics (ami...

In studies of the interactions of antibacterial agents, it became important to try to elicit bacterial resistance to antibiotics in the experimental animal. Since this proved to be unexpectedly difficult, attention was directed to the process by which bacteria acquire resistance during exposure in vivo. The present paper is concerned with the incidence of streptomycin resistance in strains of s...

The worrying appearance of microbial resistance to antibiotics is a worldwide problem which needs to be tackled urgently. Microbial resistance to the common classes of antibiotics involving purely organic compounds unfortunately develops very rapidly and in most cases, resistance was detected soon after or even before release of the antibiotic to the market. Therefore, novel concepts for antibi...