Background: Type 1 diabetes mellitus (T1DM) as an autoimmune disorder is associated with other autoimmune diseases such as autoimmune thyroid (AIT) disease. The aim of this study was to determine the prevalence of AIT in children who were referred to Amirkola Endocrine Clinic (north of Iran). Methods: This cross-sectional study was carried out on 100 diabetic children aged 1-15 years during ...

introduction : in order to evaluate the role of thyroid autoimmunity in patients with goiter, this study was done 10 years after implementation of iodine supplementation program ( iodised salt). the serum levels of thyroid peroxidase antibodies (anti tpo) and thyroglobulin antibodies (anti tg) were studied in a group of patients with simple goiter and compared with normal controls. materials an...

INTRODUCTION Autoimmune diseases are complex diseases with genetic, endogenous and environmental etiologies. Viral infections have been postulated as one of the factors that may be the trigger of autoimmune diseases. METHODOLOGY Thyroid peroxidase (TPO) and thyroglobulin (TG) antibodies were measured before thyroidectomy in 100 subjects by chemiluminescence method, 50 of whom were autoimmune ...

OBJECTIVE Untreated maternal hypothyroidism during pregnancy can have adverse consequences on maternal health and child intelligence quotient (IQ). Our objective was to examine the cost-effectiveness of screening pregnant women for autoimmune thyroid disease. DESIGN We developed a state-transition Markov model and performed a cost-effectiveness analysis of screening pregnant US women, aged 15...

BACKGROUND/AIMS There have been controversial reports linking Helicobacter pylori infection to autoimmune thyroid disease (AITD). However, data regarding the relationship are limited for Asian populations, which have an extremely high prevalence of H. pylori infection. We performed this study to investigate the association between H. pylori infection and AITD in Koreans. METHODS This study in...

BACKGROUND Complex bidirectional relationships have been described between body weight, thyroid function, and risk of thyroid disorders, including thyroid autoimmunity. We used a life-course approach to examine the potential association of childhood or adult body weight with the risk of thyroid autoimmunity and other thyroid disorders at age 60-64 years in a large population-based birth cohort ...

The exact influences of thyroid functions on body mass index Background: (BMI) are ill-defined in euthyroid pregnant women with gestational diabetes mellitus (GDM). To investigate the effect of GDM on maternal thyroid functions and Objectives: BMI. A casecontrol study was conducted in Saad Abualila Hospital, Methods: Khartoum, Sudan June to August 2015. Cases included women with GDM and healthy...

This radioimmunoassay was developed for specific and large-scale routine measurement of autoantibodies to thyroperoxidase (TPO), an enzyme recently identified as the thyroid microsomal antigen. Because of the scarcity of purified thyroperoxidase, we did not base the assay on the antigen-coated method but rather on autoantibody inhibition of the binding of labeled TPO to a solid-phase-bound mono...