نتایج جستجو برای: anti nuclear antibody
تعداد نتایج: 700264 فیلتر نتایج به سال:
Abstract Background and Objectives There are many antibodies and antigens that cause blood group related transfusion reactions. In this study we aim to find the prevalence of blood group antibodies in patients at different ages and with different gender. Materials and Methods In this descriptive study, we screened 30659 patients (59% female and 41% male, age range 1-85) referring to differ...
We have obtained a polyclonal antibody that recognizes a major polypeptide component of chicken mitotic chromosome scaffolds. This polypeptide migrates in SDS PAGE with Mr 170,000. Indirect immunofluorescence and subcellular fractionation experiments confirm that it is present in both mitotic chromosomes and interphase nuclei. Two lines of evidence suggest that this protein is DNA topoisomerase...
Despite the major advances in conventional forms of treatment (i.e. surgical techniques, radiotherapy and chemotherapy) and improved survival rates, cancer is still the second leading cause of death in developing countries. One major limitation of cytotoxic drugs and radiation in the treatment of cancer patients is their inability to discriminate between malignant and normal tissues. This in tu...
Methods: Treatment naive CHC patients were enrolled. They were classified into 2 groups according to presence or absence of PHT. Patients were subjected to liver function tests (LFTs), hepatitis C virus antibody (HCV-Ab), hepatitis B surface antigen (HBs-Ag), anti-nuclear antibody (ANA), Bilharzial agglutination titer, ultrasound abdomen and oesophago-gastro-duodensocpy. Egy-Score, ASTto-Platel...
background: selective antibody deficiency with normal immunoglobulins (sadni) may be identified as part of distinct primary or secondary immunodeficiency disorders. the clinical manifestations include recurrent, often severe or prolonged, upper or lower respiratory tract infections. objectives: to evaluate sadni in patients with recurrent sinopulmonary infections and its relation to igg subclas...
abstract autoimmune pancreatitis (aip) is a rare disorder that may be present as common bile duct stricture. the patient was a seventy-year-old man with presentations as recurrent abdominal pain and jaundice, elevated billirobin (bil) and elevated alkaline phosphatase (alkp) in association with the presence of hetrogenesity of the pancreatic head and dilated intra and extra hepatic bile ducts i...
background: anti-thyroid peroxidase antibody (anti-tpo antibody) is a member of thyroid autoantibodies which are important in inducing and also diagnosing autoimmune thyroid diseases. thyroid autoimmunity can cause several forms of thyroiditis and abnormal thyroid functions, ranging from hypothyroidism to hyperthyroidism. objective: to evaluate the relationship between serum levels of anti-tpo ...
BACKGROUND Serum samples from patients with autoimmune connective tissue diseases that show a finely speckled antinuclear antibody (ANA) on indirect immune-fluorescence often have antibodies against unknown nuclear target antigens. To search for such autoantigens we applied a proteomic approach using sera from patients with a high ANA titer (>or=640) and finely speckled fluorescence but in whom...
It was previously demonstrated that monoclonal antibody CC-3 binds to a phosphorylation dependent epitope present on a 255 kDa nuclear protein (p255). We show here that in interphase cells, p255 distributes to typical nuclear speckles that correspond to the localization of spliceosome components as revealed by antibodies to the m3G cap of snRNAs or to the non-snRNP splicing factor SC-35. Immuno...
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