Epilepsies of surgical interest are focal and drug-resistant forms associated with various different conditions (malformations, stroke, tumors, infectious and/or inflammatory processes, brain injuries). There is mounting evidence that early resective surgery can achieve seizure-free status or reduce seizure frequency. The main challenge in the presur‐ gical assessment of patients with epilepsy ...

An association between acute CNS infections and seizures is reported in the literature. The etiology of these seizures is, in some cases, precipitated by epileptogenic pathogenesis of the infectious agent in the brain parenchyma. A different etiology of seizures as a consequence of infections, independent of the infectious agent, relates to the inflammatory reaction. Thirdly, the febrile respon...

Here we present a unique, but important seizure variant directly related to placement of subdural grids. Two distinct epileptogenic zones were identified, one which correlated with the patient's baseline seizures and a separate zone associated with atypical semiology and localization. Inspection of this zone at surgery revealed cortical deformation from the grid itself. The patient underwent su...

Investigators from University of California Los Angeles, studied whether epileptogenic tubers in Tuberous Sclerosis Complex (TSC) can be identified by diffusion tensor imaging (DTI).

This report describes the long-term follow-up of 56 patients with refractory partial epilepsy who, within 3 months of vigabatrin add-on therapy (3 g/day), showed a reduction in monthly seizure frequency of more than 50%. The short-term (6 months) and long-term (5 years) effects of vigabatrin on seizure frequency in this patient cohort have been published separately. The reduction in seizure fre...

Focal cortical dysplasia (FCD) is one of the most common epileptogenic lesions associated with development malformations. However, accurate detection FCD relies on radiologist professionalism, and in many cases, lesion could be missed. In this work, we solve problem automatic identification magnetic resonance images (MRI). For task, improve recent methods Deep Learning-based apply it for a data...

Spatially extended excitable systems exhibit a variety of spatiotemporal dynamics — from stable to chaotic. These dynamics can change under pathological conditions and impair normal functions. Thus being able to control the altered dynamics for improved functioning has potential for wide ranging applications in real and artificial systems. Here we propose a simple and general method that can be...

Toxoplasmosis is a rare disease caused by intracellular protozoan parasite, Toxoplasma gondii. Though most patients with toxoplasmosis are asymptomatic, congenital toxoplasmosis in the fetus can cause ocular involvement such as chorioretinitis and central nervous system disease including intracerebral calcification, nystagmus, hydrocephalus and microcephaly. Also, these brain lesions can cause ...