Results of cholinesterase, dibucaine and fluoride numbers, and scoline hydrolysis rates are presented in a family found to have normal, silent and abnormal genes for plasma cholinesterase. Five sibs, confirmed by red cell grouping and tissue typing, have been shown to possess a cholinesterase pattern which cannot be explained on the basis of accepted theories of inheritance. In view of this it ...

OBJECTIVE To describe the methods and patient characteristics of the Canadian Outcomes Study in Dementia (COSID). METHODS COSID is a 3-year prospective study of dementia patients living in the community at the time of study registration. We assessed patients' cognition, behaviour, and functioning every 6 months, using the Modified Mini-Mental State Examination (3MS), the Neuropsychiatric Inve...

In this research, we synthesized oxazine and thiazine derivatives (3-6). These of chacone compounds (1 2) that from 4- hydroxyacetophenone aldehyde such as, 4-bromobenzaldehyde chlorobenzaldehyde. chalcone (1-2) reacted with urea to produce as 4-[4-amino-6-(4-subsutitedphenyl)-2H-1,3-oxazin-2-yl] phenol (3 4) thiourea 4-[4-amino-6-(4-subsutitedphenyl)-2H-1,3-thiazin-2-yl] (5 6). were characteri...

INTRODUCTION Malathion is one of organophosphate poisons (OPPs) that inhibit cholinesterase activity and induce oxidative stress in target organs, such as the reproductive system. The aim of this study was to assess the effects of Malathion on serum and erythrocyte cholinesterase activity in male rats and also to assess the protective effects of vitamin C in this regard. METHODS This experime...

Hypertension, also known as high or raised blood pressure, is a multifactorial disease with multiple causes and treatments. The prevalence of hypertension in the urban Indian population was estimated to be 40.8% rural 17.9%. Though there are treatment still it challenge manage this effectively lower side effects all available treatments full toxic effects. NIA/DG/2020/01 new anti-hypertensive A...

Abstract. Arab Y, Sahin B, Ceylan O, Zellagui A, Olmez OT, Kucukaydin S, Tamfu AN, Ozturk M, Gherraf N. 2022. Assessment of in vitro activities and chemical profiling Senecio hoggariensis growing Algerian Sahara. Biodiversitas 23: 3498-3506. The antioxidant, anticholinesterase, tyrosinase inhibitory, antibiofilm, anti-quorum sensing the ethyl acetate extract hoggariensis,growing Sahara, were st...

Cholinesterase inhibitors are the only approved drug treatment for patients with mild to moderately severe Alzheimer's disease. Interestingly, the clinical potency of these drugs does not correlate well with their activity as cholinesterase inhibitors, nor is their action as short lived as would be expected from purely symptomatic treatment. A few cholinesterase inhibitors, including galantamin...