نتایج جستجو برای: anthrax spore
تعداد نتایج: 13072 فیلتر نتایج به سال:
Bacillus anthracis is a spore-forming bacterium that causes anthrax in humans and in other mammals. The glycoprotein BclA (Bacillus collagen-like protein of anthracis) is a major constituent of the exosporium, the outermost surface of B. anthracis spores. The glycosyl part of BclA is an oligosaccharide composed of 2-O-methyl-4-(3-hydroxy-3-methylbutanamido)-4,6-dideoxy-d-glucose, referred to as...
We previously showed that a multiple antigenic peptide (MAP) vaccine displaying amino acids (aa) 304 to 319 from the 2β2-2β3 loop of protective antigen was capable of protecting rabbits from an aerosolized spore challenge with Bacillus anthracis Ames strain. Antibodies to this sequence, referred to as the loop-neutralizing determinant (LND), are highly potent at neutralizing lethal toxin yet ar...
STUDIES ON BLOOD-BRAIN BARRIER DISRUPTION IN ANTHRAX MENINGITIS Dhritiman V. Mukherjee, Ph.D. George Mason University, 2009 Dissertation Director: Dr. Serguei G. Popov B. anthracis causes hemorrhagic meningitis. The pathogenesis and molecular mechanisms associated with blood-brain barrier (BBB) dysfunction in anthrax meningitis remain poorly understood. We reported previously that anthrax-secre...
Anthrax is a zoonotic disease that occurs naturally in wild and domestic animals but has been used by both state-sponsored programs and terrorists as a biological weapon. A Soviet industrial production facility in Sverdlovsk, USSR, proved deficient in 1979 when a plume of spores was accidentally released and resulted in one of the largest known human anthrax outbreaks. In order to understand th...
Recombinant Bacillus subtilis endospores have been used to vaccinate against tetanus and anthrax. In this work, we have developed spores that could be used to vaccinate against Clostridium perfringens alpha toxin and that could be used to protect against gas gangrene in humans and necrotic enteritis in poultry. The primary active agent in both cases is alpha toxin. A carboxy-terminal segment of...
Background and purpose: Ânthrax is a zoon otic disease common between animals and man which is caused by a gram positive spore forming bacillus, known as Bacillus Ânthracis. This disease is still one of the causes of health problems in developing countries. Çhahar Mahal Bakhtyari state is one of the agricultural and animal breeding centers of Ïran and annually many of the human and anim...
Background: Anthrax is a zoonotic infectious disease caused by Bacillus anthracis. Investigating the spatiotemporal characteristics of anthrax and impact meteorological factors on incidence helpful for prevention control anthrax. Methods: At first, we applied Granger causality test to explore transmission between counties cities Gannan Tibetan Autonomous Prefecture, Gansu P...
Bacillus anthracis, a Gram-positive spore forming rod-shaped bacteIn this issue of EBioMedicine, Keim and colleagues (Keim et al., rium, is the causative agent of anthrax. This zoonotic disease principally affects herbivores but B. anthracis can also infect other livestock and wildlife species (WHO, 1998). Human cases mainly occur sporadically and infectionsmostly follow direct or indirect cont...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید