نتایج جستجو برای: anterior optic neuritis
تعداد نتایج: 172868 فیلتر نتایج به سال:
The discovery of papilledema in children constitutes a neuroophthalmological emergency; the purpose this report is to help differentiate MOGAD from other differential diagnosis bilateral optic neuritis, especially childhood.
Program Number: 5528 Poster Board Number: B0099 Presentation Time: 8:30 AM–10:15 AM Neuroprotective Effects of Amnion-derived Cellular Cytokine Solution (ACCS) in Experimental Optic Neuritis Reas Sulaimankutty1, Kimberly Dine1, Helayna Brown1, Larry R. Brown2, Kenneth S. Shindler1. 1Ophthalmology, Univ of Pennsylvania, Scheie Eye Inst, Philadelphia, PA; 2Stemnion Inc, Pittsburgh, PA. Purpose: O...
BACKGROUND Complement mediated autoimmunity against aquaporin-4 results in astrocytic damage in neuromyelitis optica (NMO). There is evidence for increased CSF glial fibrillary acidic protein (GFAP) and S100B levels in acute NMO. Here we tested whether the CSF finding also holds true for the diagnostic value of serum GFAP and S100B levels in NMO. METHODS A multicentre study included 322 patie...
Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography
Neuromyelitis optica (NMO) is an inflammatory autoimmune disease of the central nervous system that preferentially targets the optic nerves and spinal cord. The clinical presentation may suggest multiple sclerosis (MS), but a highly specific serum autoantibody against the astrocytic water channel aquaporin-4 present in up to 80% of NMO patients enables distinction from MS. Optic neuritis may oc...
A rare case of bilateral optic neuritis is presented in a child with no light perception. Ophthalmic examination revealed dilated pupils without reaction to the light, swollen optic discs with small peripapillary hemorrhages in both eyes. Serology revealed evidence of recent Epstein-Barr virus infection. After treatment with high dose of corticosteroid visual acuity gradually improved. After fo...
BACKGROUND To compare the mean central macular thickness (CMT) and the mean average optic nerve retinal nerve fiber layer (RNFL) thickness in the eyes of patients with a history of optic neuritis and/or multiple sclerosis (MS) using 5 commercially available optical coherence tomography (OCT) instruments. METHODS Cross-sectional study including 46 patients (92 eyes) with a history of optic neu...
BACKGROUND Inflammation of the optic nerve is a common cause of visual loss due to optic nerve pathology. OBJECTIVE To report the clinical features, demographic pattern and response to pulse steroid therapy in patients with idiopathic optic neuritis in eastern Nepal. MATERIALS AND METHODS The hospital data of patients with idiopathic optic neuritis admitted to the department of ophthalmolog...
The effect of increasing temporal frequency on contrast sensitivity anomalies in unilateral optic neuritis has been investigated. For 4 c/deg gratings no change in the deficit was observed at any temporal frequency whereas there was a tendency for the deficit to decrease with increase in temporal frequency for 0-5 c/deg gratings. The latter effect was not observed in a case of optic neuritis wi...
BACKGROUND AND PURPOSE There is a well-known relationship between MS and damage to the optic nerve, but advanced, quantitative MR imaging methods have not been applied to large cohorts. Our objective was to determine whether a short imaging protocol (< 10 minutes), implemented with standard hardware, could detect abnormal water diffusion in the optic nerves of patients with MS. MATERIALS AND ...
OBJECTIVE To identify factors associated with a high and low risk of developing multiple sclerosis after an initial episode of optic neuritis. METHODS Three hundred eighty-eight patients who experienced acute optic neuritis between July 1, 1988, and June 30, 1991, were followed up prospectively for the development of multiple sclerosis. Consenting patients were reassessed after 10 to 13 years...
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