Buprenorphine is a partial mu receptor agonist and kappa/delta antagonist commonly used for the treatment of opioid dependence or as an analgesic. It has a long plasma half-life and a high binding affinity for opioid receptors. This affinity is so high, that the effects are not easily antagonized by competitive antagonists, such as naloxone. The high affinity also prevents binding of other opio...

the intraoperative care of pheochromocytomas can be difficult and lead to serious complications. we present a case of a 46 year-old female undergoing laparoscopic resection of pheochromocytoma, who was scheduled for surgery with phenoxybenzamine and amlodipin. under general anesthesia cardiovascular stability was achieved by peritumoral infiltration of lidocaine during resection.

The growing importance of ambulatory surgery during the past decade has led to the development of efficient anesthetic techniques in terms of quality and safety of anesthesia and recovery. In these challenging objectives, intravenous techniques have played an important role, as they provide safe, efficient, and cost-effective anesthesia in the ambulatory setting. Among the numerous intravenous ...

Patients undergoing surgical correction of scoliosis present many challenges to anesthetists because of the pathophysiologic derangements caused by the disease and the demanding nature of the anesthetic care that is required. A thorough understanding of the pathophysiology of the disease, intraoperative concerns specific to the procedure, and the efficacy of various anesthetic management techni...

Severe aortic stenosis combined with coronary heart disease remarkably increases the risk of perioperative morbidity and mortality during noncardiac surgery. Surgery and anesthesia often complicate the perioperative outcome if adequate monitoring and proper care are not taken. Therefore, understanding of the hemodynamic changes and anesthetic implications is an important for successful perioper...

INTRODUCTION Awake craniotomy allows continuous monitoring of patients' neurological functions during open surgery. Anesthesiologists have to sedate patients in a way so that they are compliant throughout the whole surgical procedure, nevertheless maintaining adequate analgesia and anxiolysis. Currently, the use of α2-receptor agonist dexmedetomidine as the primary hypnotic-sedative medication ...

many of injured children will require surgical treatment with involvement of the anesthesiologist. the anesthesia providers may have to take care of pediatric patients on following occasions: 1- initial stabilization in the emergency department 2- providing sedation and monitoring for imaging 3- preoperative management of emergent surgical procedures such as laparotomy or craniotomy 4- manageme...

Background Advances in surgical and anesthetic techniques combined with sophisticated perioperative monitoring are factors that have contributed to an expanding number of older adults undergoing surgery. Older persons often have multiple comorbid conditions that limit their functional capacity and increase the risk of death. An initial complication is much more likely to lead to other complicat...

Learning Objectives: After reading this article, the participant should be able to: 1. Recall the incidence and differential diagnosis offoramen magnum meningiomas. 2. Describe the clinical presentation and the pre-operative evaluation ofpatients with foramen magnum meningiomas, including the radiologic features and the different types offoramen magnum meningiomas. 3. Explain the pre-operative ...

Interventional neuroradiologic procedure represents treatment of central nervous system disease by endovascular access for the purpose of delivering therapeutic agents, including both drugs and devices. For optimal anesthetic management, anesthesiologists should be familiar with specific radiological procedures and their potential complications. This article provides a brief overview of special...