نتایج جستجو برای: and insulin resistance in obese

تعداد نتایج: 21786252  

ژورنال: پژوهش در پزشکی 2015

Background: Chemerin is a new adipokine, which is involved in inflammation and resistance insulin development. Thus, recent study examined changes of chemerin plasma levels and insulin resistance in two groups of healthy and insulin resistance male rats after 8 weeks resistance training. Materials and methods: 32 male Wister rats with a weight, 161 ± 23 g were randomly divided into four groups ...

Background and Objectives: The P53 is one of the genes involved in weight management. This study investigated associations of dietary intakes, anthropometric measurements and insulin resistance with relative P53 gene expressions.  Materials & Methods: Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were collected from 151 individuals, aging nearly 40 years, who underwent el...

Journal: :Archives of andrology 2006
J A Osuna R Gómez-Pérez G Arata-Bellabarba V Villaroel

The objective of this work was to evaluate the relationship between sex steroid hormones, sex hormone-binding-globulin, leptin, insulin and insulin resistance in obese men. Anthropometrical indexes, total testosterone (Tt), free testosterone (fT), estradiol (E), sex hormone-binding-globulin (SHBG), glucemia, insulin and leptin were measured in 77 men, with ages between 20 and 60 years. Accordin...

Journal: :Archives of pediatrics & adolescent medicine 2009
Julien Aucouturier Martine Meyer David Thivel Michel Taillardat Pascale Duché

BACKGROUND Upper body fat distribution is associated with the early development of insulin resistance in obese children and adolescents. OBJECTIVE To determine if an android to gynoid fat ratio is associated with the severity of insulin resistance in obese children and adolescents, whereas peripheral subcutaneous fat may have a protective effect against insulin resistance. SETTING The pedia...

Journal: :African health sciences 2014
Zehra Esra Onal Vildan Atasayan Tamay Gürbüz Evrim Hepkaya Cağatay Nuhoğlu

OBJECTIVES We investigated the relationship between insulin resistance reflected by homeostasis model assessment (HOMA-IR) index and serum HbA1c levels of obese children. MATERIAL AND METHODS This study included 70 obese and 60 normal weight healthy children between the ages of 3 and 15. Anthropometric measures and biochemical tests (fasting glucose, fasting insulin, HbA1c) were performed on ...

Journal: :British journal of pharmacology 1999
D W Laight K M Desai N K Gopaul E E Anggård M J Carrier

We investigated the ability of an acute pro-oxidant challenge in vivo to deteriorate glycaemic control and insulin action in the obese Zucker rat, a model of insulin resistance associated with oxidant stress. In obese animals, the daily administration for 1 week of hydroquinone (HQ) in combination with L-buthionine sulphoximine (BSO), elevated fasting plasma glycaemia and insulinaemia and marke...

Journal: :American journal of physiology. Endocrinology and metabolism 2000
A Suga T Hirano H Kageyama T Osaka Y Namba M Tsuji M Miura M Adachi S Inoue

To determine the influence of dietary fructose and glucose on circulating leptin levels in lean and obese rats, plasma leptin concentrations were measured in ventromedial hypothalamic (VMH)-lesioned obese and sham-operated lean rats fed either normal chow or fructose- or glucose-enriched diets (60% by calories) for 2 wk. Insulin resistance was evaluated by the steady-state plasma glucose method...

Journal: :Hong Kong medical journal = Xianggang yi xue za zhi 2014
H Y Ng Jack H M Young K F Huen Louis T W Chan

OBJECTIVES. To investigate the demographic characteristics and insulin resistance in local overweight/obese Chinese children with and without acanthosis nigricans, and the associations of acanthosis nigricans with insulin resistance and other cardiometabolic co-morbidities. DESIGN. Case series with cross-sectional analyses. SETTING. A regional hospital in Hong Kong. PATIENTS. Chinese children a...

Journal: :Journal of Student Research 2023

The rising global prevalence of obesity presents a diminished quality life and expectancy. Though myriad factors contributes to obesity, one the leading is excessive adipose tissue accumulation increases body’s production leptin satiety hormone resulting in resistance. Leptin resistance results increased vulnerability through improper regulation insulin, decline metabolic functions, decreased s...

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