نتایج جستجو برای: and among als inhibitors

تعداد نتایج: 16979356  

پایان نامه :0 1375

investigation the archetype of mother can help the reader to understand poes works, especially his fiction, better, if not fully. motivated by internal and external drives to get into the universe in its manifold form poe was impelled to art and, from various modes of art, to symbolism. how much was poe successful to produce works of art has been a matter of dispute among critics. however, ther...

Journal: :Archives italiennes de biologie 2011
Michela Ferrucci Fedrica Fulceri Luca Toti Paola Soldani Gabriele Siciliano Antonio Paparelli Francesco Fornai

In the present review a large amount of experimental and clinical studies on ALS are discussed in an effort to dissect common pathogenic mechanisms which may provide novel information and potential therapeutic strategies for motor neuron degeneration.Protein clearing systems play a critical role in motor neuron survival during excitotoxic stress, aging and neurodegenerative disorders. Among var...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - پژوهشکده ادبیات 1393

1.0 overview it seems that grammar plays a crucial role in the area of second and foreign language learning and widely has been acknowledged in grammar research. in other words, teaching grammar is an issue which has attracted much attention to itself, and a lot of teachers argue about the existence of grammar in language teaching and learning. this issue will remind us a famous sentence f...

2003
Sung-Ho Kim En-Joung Park Sung-Sook Yoon Jung-Do Choi

Acetolatate synthase(ALS) catalyzes the first common step in the biosynthesis of valine, leucine, isoleucine in plants and microorganisms. ALS is the target of several classes of herbicides, including the sulfonylureas, the imidazolinones, and the triazolopyrimidines. To elucidate the roles of arginine residues in tobacco ALS, chemical modification and site-directed mutagenesis were performed. ...

Journal: :Journal of Bioscience and Bioengineering 2021

Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron loss in the brain and spinal cord; however, its etiology unknown, no curative treatment exists. TAR DNA-binding protein 43 (TDP-43), encoded TARDBP, a genetic mutation observed 2–5% of familial ALS, TDP known to be mislocalized cytoplasm. This study aimed identify compounds that inhibited nuclear cytoplasmic locali...

2013
Ching-Piao Tsai Bo-Hsiung Chang Charles Tzu-Chi Lee

BACKGROUND Few studies have assessed cause of death among patients with amyotrophic lateral sclerosis (ALS). We investigated underlying cause and place of death among patients with ALS in Taiwan during 2003-2008. METHODS The data source was the Taiwan National Health Insurance database for the period 2003-2008. In total, 751 patients older than 15 years with a primary diagnosis of ALS were in...

Journal: :journal of cell and molecular research 0

monoamine oxidase (ec, 1.4.3.4) or amine oxidoreductase catalyzes the oxidative deamination of biogenic amines. abnormal action of the monoamine oxidase b has been associated with neurological dysfunctions including parkinson´s disorder. monoamine oxidase b inhibitors divulged that these agents were effective in the therapeutic management of parkinson's disease. understanding the interaction of...

ژورنال: مجله دندانپزشکی 2019

Background and Aims: Candida is an opportunistic pathogen that causes illness in people with a defective or weakened condition. Infectious diseases (periodontal diseases) are inflammatory and malignant inflammation of the dental-gum complex, in which the growth of biofilms caused by Candida glabrata, Parapseilosis and Tropikalis is less than Candida albicans. Brown algae Sargasum is more compat...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده ادبیات و زبانهای خارجی 1391

building on previous studies on intellectual features and learners’ grammar learning, the present study aimed at investigating whether intelligence criterion had any impact on efl learners’ english grammar learning across two intelligence levels. in the current study, the participants were divided into two experimental and control groups by administration of raven i.q. test. this led to the for...

2014
Janice Du Mont Tonia Forte

BACKGROUND There is strong evidence that women with serious or chronic mental illness experience higher rates of violence than women in the general population. Our objective was to examine the risk of intimate partner violence (IPV), a form of violence that is often recurrent and linked to negative physical and psychological consequences, among a representative sample of non-institutionalized w...

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