نتایج جستجو برای: anaplasma phagocytophilum

تعداد نتایج: 1959  

Journal: :The Journal of clinical investigation 2010
Girish Neelakanta Hameeda Sultana Durland Fish John F Anderson Erol Fikrig

In the United States, Ixodes scapularis ticks overwinter in the Northeast and Upper Midwest and transmit the agent of human granulocytic anaplasmosis, Anaplasma phagocytophilum, among other pathogens. We now show that the presence of A. phagocytophilum in I. scapularis ticks increases their ability to survive in the cold. We identified an I. scapularis antifreeze glycoprotein, designated IAFGP,...

2005
Stanka Lotric-Furlan Miroslav Petrovec Tatjana Avsic-Zupanc Franc Strle

We report a patient with febrile illness and epidemiologic and clinical findings consistent with human granulocytic ehrlichiosis and tickborne encephalitis, in whom infection with Anaplasma phagocytophilum was demonstrated by polymerase chain reaction and seroconversion. Tickborne encephalitis virus infection was established by serum immunoglobulin (Ig) M and IgG antibodies.

Journal: :PLoS Pathogens 2009
Qingming Xiong Mingqun Lin Yasuko Rikihisa

In eukaryotes, intracellular cholesterol homeostasis and trafficking are tightly regulated. Certain bacteria, such as Anaplasma phagocytophilum, also require cholesterol; it is unknown, however, how this cholesterol-dependent obligatory intracellular bacterium of granulocytes interacts with the host cell cholesterol regulatory pathway to acquire cholesterol. Here, we report that total host cell...

Journal: :Journal of clinical microbiology 2011
Wiebke Scharf Sonja Schauer Felix Freyburger Miroslav Petrovec Daniel Schaarschmidt-Kiener Gabriele Liebisch Martin Runge Martin Ganter Alexandra Kehl J Stephen Dumler Ana L Garcia-Perez Jennifer Jensen Volker Fingerle Marina L Meli Armin Ensser Snorre Stuen Friederike D von Loewenich

Anaplasma phagocytophilum is a gram-negative, tick-transmitted, obligate intracellular bacterium that elicits acute febrile diseases in humans and domestic animals. In contrast to the United States, human granulocytic anaplasmosis seems to be a rare disease in Europe despite the initial recognition of A. phagocytophilum as the causative agent of tick-borne fever in European sheep and cattle. Co...

Journal: :Blood 2003
Jason A Carlyon Mustafa Akkoyunlu Lijun Xia Tadayuki Yago Tian Wang Richard D Cummings Rodger P McEver Erol Fikrig

Anaplasma phagocytophilum causes human granulocytic ehrlichiosis, the second most common tick-borne disease in the United States. Mice are natural reservoirs for this bacterium and man is an inadvertent host. A phagocytophilum's tropism for human neutrophils is linked to neutrophil expression of P-selectin glycoprotein ligand-1 (PSGL-1), as well as sialylated and alpha1,3-fucosylated glycans. T...

Journal: :Biomedical and environmental sciences : BES 2013
Qin Hao Zhen Geng Xue Xia Hou Zhen Tian Xiu Jun Yang Wei Jia Jiang Yan Shi Zhi Fei Zhan Guo Hua Li De Shan Yu Hua Yong Wang Jian Guo Xu Kang Lin Wan

OBJECTIVE Lyme disease and Human granulocytic anaplasmosis are tick-borne diseases caused by Borrelia burgdorferi and Anaplasma phagocytophilum respectively. We have investigated infection and co-infection of the two diseases in the population of forest areas of eight provinces in China by measuring seroprevalence of antibodies against B. burgdorferi and A. phagocytophilum. METHODS Forest are...

Journal: :Journal of the South African Veterinary Association 2014
Lorelei L Clarke Lora R Ballweber Kelly Allen Susan E Little Michael R Lappin

Ticks, sera and ethylenediaminetetraacetic acid (EDTA) blood were collected from dogs evaluated at the Amakom Veterinary Clinic in Kumasi, Ghana. Sera were evaluated for Dirofilaria immitis antigen and antibodies against Borrelia burgdorferi, Anaplasma phagocytophilum and Ehrlichia canis. Conventional polymerase chain reaction assays designed to amplify the deoxyribonucleic acid (DNA) of Ehrlic...

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