نتایج جستجو برای: amphotericin
تعداد نتایج: 7081 فیلتر نتایج به سال:
Pseudohyperphosphatemia due to an interaction between liposomal amphotericin B and the Beckman Coulter PHOSm assay occurs sporadically and remains underrecognized in clinical practice. This retrospective case-control study compares the incidences of hyperphosphatemia in adult inpatients exposed to liposomal amphotericin B or a triazole. A case series of patients with confirmed pseudohyperphosph...
BACKGROUND Whether outcome of central nervous system (CNS) cryptococcosis in solid organ transplant recipients treated with lipid formulations of amphotericin B is different from the outcome of the condition treated with amphotericin B deoxycholate (AmBd) is not known. METHODS We performed a multicenter study involving a cohort comprising consecutive solid organ transplant recipients with CNS...
Combinations of antimicrobial agents were tested against 35 strains of zygomycetes. The interaction between amphotericin B and rifampin was synergistic or additive. Flucytosine alone was inactive and, upon combination with amphotericin B, synergy was not achieved. The combination of amphotericin B with terbinafine was synergistic for 20% of strains, and the interaction between terbinafine and v...
A case of aspergillus tracheobronchitis following influenza A infection in an immunocompetent 35 year old woman is described that required prolonged mechanical ventilation for airways obstruction. Treatment included liposomal amphotericin, inhaled amphotericin, gamma interferon and GM-CSF. Liposomal amphotericin therapy was associated with reversible hepatosplenomegaly. Inhaled corticosteroids ...
Dermostatin is a polyene antibiotic which possesses a typical spectrum of antimicrobial activity. In vivo, by parenteral or oral administration, dermostatin was less effective than amphotericin B against Candida albicans. The in vivo activity of dermostatin was comparable to amphotericin B against Cryptococcus neoformans and Blastomyces dermatitidis ; amphotericin B was more effective than derm...
Amphotericin B derivatives, such as MS-8209, have been evaluated as a therapeutic approach to human immunodeficiency virus (HIV) infection. We show that MS-8209, like amphotericin B, increases tumor necrosis factor alpha (TNF-alpha) mRNA expression and TNF-alpha production and consequently HIV replication in human macrophages. These effects confirm the pharmacological risk associated with the a...
A case of aspergillus tracheobronchitis following influenza A infection in an immunocompetent 35 year old woman is described that required prolonged mechanical ventilation for airways obstruction. Treatment included liposomal amphotericin, inhaled amphotericin, gamma interferon and GM-CSF. Liposomal amphotericin therapy was associated with reversible hepatosplenomegaly. Inhaled corticosteroids ...
An amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane.
Amphotericin B is an antimycotic agent extracted and isolated from a soil streptomycete and is currently in clinical use against chronic fungal infections. An enormous amount of data on the biological activity of this polyketide has been accumulated, which underlines the potency and effectiveness of the medicament, as well as its importance in membrane research. Even so, after five decades of i...
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