The present work aimed at preparing films of amlodipine with the reason of developing a dosage from for a very fast onset of action, which is beneficial in managing servere conditions of hypertension, aiding in the enhancement of bioavailability, and is very convenient for administration, without the problem of swallowing and using water. Amlodipine is a calcium channel blocker that dilates (wi...

Objective- This study investigated the effect of amlodipine on intestinal ischemia-reperfusion injury in ratsDesign-Experimental studyAnimals-Fifteen male Sprague-Dawly rats weighing 200-220gProcedure- Rats were randomly divided into 3 groups: IR group (operation with clamping), sham group (operation without clamping), and IRA group (operation with clamping and 5mg/kg amlodipi...

Two rapid assay procedures based on visible spectrophotometry and high performance liquid chromatography (HPLC) have been developed for the determination of amlodipine besylate (ADB) in pharmaceutical formulations. Spectrophotometric method is based on the bromination of ADB with a known excess of bromate-bromide mixture in acid medium followed by the determination of surplus bromine by reactin...