The addition of bis(pinacolato)diboron [(Me4C2O2)B-B(O2C2Me4)] to α,β-unsaturated carbonyl compounds giving β-boryl carbonyl compounds and the addition to terminal alkynes yielding either 2-boryl-1-alkenes or 1-boryl-1-alkenes were carried out in DMF at room temperature in the presence of CuCl and AcOK. The transmetalation between diboron and [Cu(Cl)OAc]K generating a borylcopper species was pr...

We report a one-pot synthesis of nitrogen heterocyclic compounds initiated by the allylation of the formyl group of bifunctional carbonyl compounds accompanying chemo-, regio-, and diastereoselective carbon-carbon bond formation in side chain moieties.

The diazo group of a series of a-diazo carbonyl compounds can be reduced to the corresponding CH2 group by Bu3SnH under Cu(acac)2-catalytic or photochemical conditions. The mechanistic aspects of this reaction were investigated in some detail, and a possible reaction pathway was discussed. q 2000 Elsevier Science Ltd. All rights reserved.

Submit Manuscript | http://medcraveonline.com carbonic acid derivatives is a method frequently used for the synthesis of pyrimidines and 1,3-thiazines [1-7]. Although these methods have been mentioned in the literature for a long time, there are only a few examples of investigation on the mechanism and the stereochemistry of reactions. Based on earlier examinations [5-7] reaction of α,β-unsatur...

The synthesis of tetranuclear gold complexes, a structurally unprecedented octanuclear complex with a planar [Au(I) 8 ] core, and pentanuclear [Au(I) 4 M(I) ] (M=Cu, Ag) complexes is presented. The linear [Au(I) 4 ] complex undergoes C-H functionalization of carbonyl compounds under mild reaction conditions. In addition, [Au(I) 4 Ag(I) ] catalyzes the carbonylation of primary amines to form ure...

Adding a small amount of fully dispersed Pt entities onto the Au surface in Au/SiO(2) catalyst is found to be an efficient approach to improve the catalytic activity of Au (up to 70-fold) for the hydrogenation of α,β-unsaturated carbonyl compounds, without alternating its selectivity towards C=O or C=C bond hydrogenation.

AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with various α,β-unsaturated carbonyl compounds under mild conditions are described, which provides a facile and efficient pathway for the synthesis of 1-alkylated isoquinoline derivatives. The method tolerates a wide range of substrates and allows for the preparation of the products of interest in moderate to excellent yields.

the wittig reaction rate can be dramatically enhanced by irradiation of the reaction mixture containing an aldehyde or ketone; methoxymethyl(triphenyl)phosphonium chloride, potassium t-butoxide, and t buoh with a commercial microwave oven. carbonyl compound are converted to witting products within three min. in good yields.

Yellow crystals of the title compound 3-amino-4-nitro-benzyl acetate, C9H10N2O4, were isolated from the reaction of acetic anhydride with (5-amino-2-nitro-phen-yl)methanol, prepared from reduction of commerically available 5-amino-2-nitro-benzoic acid with borane-THF. The mol-ecule is essentially planar (r.m.s. deviation = 0.028 Å). The mol-ecules are linked by inter-molecular N-H⋯O hydrogen-bo...

In the title compound, C(16)H(13)N(7)O, the 1,2,4-triazolo[1,5-a][1,3,5]triazine heterocyclic system is essentially planar (r.m.s. deviation = 0.0375 Å). The attached benzene ring lies almost in the mean plane of 1,2,4-triazolo[1,5-a][1,3,5]triazine [dihedral angle = 1.36 (23)°], while the pyridine ring is turned out of this plane by the amino-methyl bridge [dihedral angle = 69.22 (9)°]. The am...