As one of the most important vesicant agents, the destructive properties of mustards on the skin, eyes and respiratory system, combined with a lack of antidote, makes them effective weapons. Such weapons are inexpensive, easily obtainable and frequently stockpiled. Sulphur mustard (mustard gas) has been used as a chemical warfare agent in at least 10 conflicts. In this article, the use of musta...

The oilseed crop improvement for Brassica rapa L. (field mustard) is considered to be important in respect of yield production coupled with unsaturated fatty acids the existing cultivars. Hence, genetic diversity, and nutritional components 14 B. cultivars were evaluated based on their attributes acid profiles at Sher-e-Bangla Agricultural University, Dhaka, Bangladesh. These differed significa...

sulfur mustard, a bifunctional alkylating agent, causes severe eye injury. the injury is a result of late inflammation, which is mediated by prostaglandins. theoretically, inhibition of prostaglandins by reagents such as indomethacine could result in alleviation of clinical adverse effects. in this study, the protective effect of topically applied indomethacine against sulfur mustard toxicity w...

Most herbivorous insect species are restricted to a narrow taxonomic range of host plant species. Herbivore species that feed on mustard plants and their relatives in the Brassicales have evolved highly efficient detoxification mechanisms that actually prevent toxic mustard oils from forming in the bodies of the animals. However, these mechanisms likely were not present during the initial stage...

Aims: To present 12 new variants of uracil mustard having drug-like properties and cytotoxic functional group, by utilizing uracil mustard (uramustine) as a lead compound. Utilize rigorous substructure and similarity of a molecular scaffold to determine drug like variants. Physicochemical properties determined indicate the variants have favorable drug-likeness. Study Design: Conduct molecular d...

Uramustine (or uracil mustard, 5-aminouracil mustard, chlorethaminacil), is an bi-functional alkylating nitrogen mustard agent that utilizes a natural product to carry the nitrogen mustard group to a selective metabolite site. The potential for applying uramustine as a therapeutic drug appeared in the 60’s, where its potential as a treatment tool for metastatic Wilms’s tumor was notes (Wilm’s t...

A greenhouse experiment was conducted to evaluate the competitive effects of different densities of wild mustardas against rapeseed. The experiment was performed in a randomized complete block design with four replicationsusing replacement series in which wild mustard and rapeseed were respectively planted in different ratios of 4:0, 3:1,2:2, 1:3 and 0:4 plants per pot. Results indicated that t...

In this study the effect of the alkylating agent, sulfur mustard, on calf thymus chromatin was investigated using UV/Vis spectroscopy, gel electrophoresis and thermal denaturation techniques. The results show that treatment of isolated chromatin with sulfur mustard releases histones from the core particles but does not affect histone H I and nonhistone chromosomal proteins. The content of ...