type 1 diabetes mellitus is frequently associated with autoimmune thyroid disease (atd).genetic susceptibility for autoantibody formation in association with atd and type 1 diabetes mellitus has been described with varying frequencies, but there is still debate about its prevailing situation in iran.  we have therefore investigated the prevalence of anti-thyroid peroxidase (anti-tpo) and anti t...

spirulina is free-floating filamentous microalgae growing in alkaline water bodies. as early as over 400 years ago, spirulina was eaten as food by the mayas, toltec’s and kanembu in mexico during the aztec civilization. spirulina is a well-known source of valuable food supplements, such as proteins, vitamins, amino acids, minerals, fatty acids, etc. it is widely used in human and animal nutriti...

background and objectives: adhesion and colonization are prerequisites for the establishment of bacterial pathogenesis. the biofilm development of pseudomonas aeruginosa was assessed on adhesive surfaces like dialysis membrane, stainless steel, glass and polystyrene. materials and methods: microtiter plate biofilm assay was performed to assess the effect of nutrient medium and growth parameters...

abstract       background and objective: glycyrrhizaglabra l. is one of the most widely used medicinal herbs in golestan province that is known for its anti-inflammatory, carminative, antiviral, anti-infection and anti-ulcer properties in iranian traditional medicine. this study aimed to assess the anti-bacterial and anti-oxidative activity of g. glabrafrom the golestan province.         method...

The effect of alcoholic extracts of leaf from Araucaria bidwillii Hook. [ABH] (Family: Araucariaceae) was evaluated in experimental models of pain and inflammation. Oral administration of 100, 200 and 300 mg/kg of leaf extracts of ABH were used for the above study. The leaf extract at 300 and 200 mg/kg showed significant reduction in acetic acid induced writhings in mice with a maximum effect o...

background: thiamine (vitb1) is a vitamin with various important physiological functions and postulated therapeutic effects.  its use as an analgesic in neuropathic pain has been undergoing in clinical settings. however, there has been little experimental investigation on this effect. in this study, anti-nociceptive and anti-inflammatory effects of thiamine were investigated in mice. methods: t...

In Iranian traditional medicine, olive has been reported to have analgesic and anti-inflamatory effects. In the present study the anti-nociceptive and anti-inflamatory effects of olive fruit has been studied. In this study the methanolic and aqueous extract of the fruit with HER (Herbal to Extract Ratio) of 4.96% and 4.84% has been used and analgesic effect of this extract has been compared wit...

Background and objectives: Positive role of saffron in human health promotion has been investigated in widespread researches. Anticancer property, neuroprotection, protection of cardiovascular system and several positive properties are reported for saffron customers. The aim of this study was assessment of saffron weakness against light damage in rat retina. Methods:</s...

In Iranian traditional medicine, olive has been reported to have analgesic and anti-inflamatory effects. In the present study the anti-nociceptive and anti-inflamatory effects of olive fruit has been studied. In this study the methanolic and aqueous extract of the fruit with HER (Herbal to Extract Ratio) of 4.96% and 4.84% has been used and analgesic effect of this extract has been compared wit...

there is the need for new drugs with better action and lesser side effects. a lot of research is being undertaken to find out new plant drugs, their extraction and pharmacological evaluation. one of such plant is curcuma aromatica whichbelongs to the genus curcuma and reported to have high ethno-botanical values in traditional medicine. the present study evaluates comparative pharmacological ac...