نتایج جستجو برای: amelogenesis
تعداد نتایج: 1829 فیلتر نتایج به سال:
Transcellular Mg(2+) transport across epithelia, involving both apical entry and basolateral extrusion, is essential for magnesium homeostasis, but molecules involved in basolateral extrusion have not yet been identified. Here, we show that CNNM4 is the basolaterally located Mg(2+) extrusion molecule. CNNM4 is strongly expressed in intestinal epithelia and localizes to their basolateral membran...
Plate I Photomicrographs of the human tooth germ. a. At the cap stage of development. The black punctate material is glycogen. b. At the bell stage of development. c. Undecalcified section illustrating the marked Schiff positivity of the odontoblast cytoplasm during dentinogenesis. d. Undecalcified section illustrating the distribution of alkaline phosphatase. Note the intense enzyme activity i...
Transforming growth factor-ß (TGF-ß) signaling plays an important role in regulating crucial biological processes such as cell proliferation, differentiation, apoptosis, and extracellular matrix remodeling. Many of these processes are also an integral part of amelogenesis. In order to delineate a precise role of TGF-ß signaling during amelogenesis, we developed a transgenic mouse line that harb...
Enamelin is an extracellular enamel matrix protein essential for normal amelogenesis. After secretion, porcine enamelin is processed to generate several enamelin-degradation products. The cumulative 32-kDa enamelin is the most abundant enamelin present, and various roles for this molecule have been suggested. However, the proteolytic cleavage sites in porcine enamelin that generate the 32-kDa e...
Purpose: Reported literature has focused largely on the early management of children and young adolescents. This article describes systematic, sequential and synchronized, psychological and restorative management of an adult patient suffering from amelogenesis imperfecta with a fairly good prognosis. The focus of this report is to attribute the specific roles of various medical and dental speci...
In this study, we analyzed the phenotype, clinical characteristics and presence of mutations in the enamelin gene ENAM in five Colombian families with autosomal dominant amelogenesis imperfecta (ADAI). 22 individuals (15 affected and seven unaffected) belonging to five Colombian families with ADAI and eight individuals (three affected and five unaffected) belonging to three Colombian families w...
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