The double-stranded RNA genome of reovirus breaks reproducibly into ten segments upon extraction from purified virions. Reovirus-induced messenger RNA's formed in infected cells correspond in length to these ten genomic segments and some real structural and biological implication must be accorded to the ready manner in which the genome is fragmented on attempted isolation. In the present work w...

The diseases caused by thrips-transmitted tospoviruses (genus Tospovirus, family Bunyaviridae) are a major constraint to production of important vegetable, legume and ornamental crops in different parts of the world. Tospoviruses are characterized by having tripartite RNA genomes and utilizing both negative and ambisense genome expression strategies. Their often wide and overlapping host ranges...

Precise control of protein and messenger RNA (mRNA) degradation is essential for cellular metabolism homeostasis. Controlled specific both molecular species necessitates their engagements with the respective machineries; this engagement involves a disordered/unstructured segment substrate traversing tunnel machinery accessing catalytic sites. However, while factors influencing have been extensi...

Avian reovirus (ARV) belongs to the genus Orthoreovirus in the family Reoviridae and was first isolated from birds in 1954 (Fahey and Crawley, 1954). Virus particles are 70 nm to 80 nm in size, non-enveloped and have icosahedral symmetry with a double-shelled arrangement of surface protein. The genome of the virus is dsRNA with 10 segments. Depending on their electrophoretic mobility the genome...