A design methodology for implementing fast, easily testable arithmetic-logic units (ALU’s) is presented. Here, we describe a set of fast adder designs, which are testable with a test set that has either ( ) complexity (Lin-testable) or (1) complexity (C-testable), where is the input operand size of the ALU. The various levels of testability are achieved by exploiting some inherent properties of...

Alu insertion polymorphisms are widely distributed in the human genome. They are readily analysed and provide an interesting set of markers for human population genetic and forensic studies. The aim of this article is to present preliminary results from our ongoing project on a survey of Alu insertion polymorphisms in various human populations. INTRODUCTION Repetitive DNA sequences comprise a s...

ABSTRAK Ayam hutan merupakan ayam leluhur dari kampung yang populasinya semakin menurun. Penelitian ini mempunyai tujuan untuk mengidentifikasi ada di pegunungan sebelah timur Kabupaten Polewal Mandar berdasarkan sifat kuantitatif diturunkan. diambil sampelnya sebanyak 30 ekor jantan dan 10 betina setiap kecamatan dengan teknik acsidental pengambilan sampel dimulai bulan Juli - Agustus 2022. Pa...

Y alphoid primers in combination with Alu and LINEs primers generated new DNA fragments in polymerase chain reactions (PCR) on DNA from a Y-only somatic cell hybrid but not from X-only, 3-only, or 21-only hybrids. X alphoid primers used in a similar manner generated new DNA fragments from the X-only hybrid, and 1 of the primers (X2) also generated new DNA fragments on 3-only and 21-only hybrids...

Primate-specific Alus harbor different regulatory features, including miRNA targets. In this study, we provide evidence for miRNA-mediated modulation of transcript isoform levels during heat-shock response through exaptation of Alu-miRNA sites in mature mRNA. We performed genome-wide expression profiling coupled with functional validation of miRNA target sites within exonized Alus, and analyzed...

Ancient Alu elements have been shown to be included in mature transcripts by point mutations that improve their 5' or 3' splice sites. We have examined requirements for exonization of a younger, disease-associated AluYa5 in intron 16 of the human ACE gene. A single G>C transversion in position -3 of the new Alu exon was insufficient for Alu exonization and a significant inclusion in mRNA was on...

DNA methylation, the only known covalent modification of mammalian DNA, occurs primarily in CpG dinucleotides. 51% of CpGs in the human genome reside within repeats, and 25% within Alu elements. Despite that, no method has been reported for large-scale ascertainment of CpG methylation in repeats. Here we describe a sequencing-based strategy for parallel determination of the CpG-methylation stat...

Power consumption and delay are two important considerations for VLSI systems which depend on various critical design parameters. The objective of this project is to reduce the power and to reduce the delay which increases the speed. The purpose of this paper is the design and implementation of an Arithmetic Logic Unit (ALU) using area optimizing techniques such as Gate Diffusion Input (GDI). I...

We have investigated the distribution of several recently inserted Alu family members within representatives of diverse human groups. Human population studies using 65 unrelated human DNA samples, as well as a familial study to test inheritance, showed that individual Alu family members could be divided into three groups. The first group consisted of relatively older Alu family members which we...

BACKGROUND Quantification of integrated proviral HIV DNA by repetitive-sampling Alu-HIV PCR is a candidate virological tool to monitor the HIV reservoir in patients. However, the experimental procedures and data analysis of the assay are complex and hinder its widespread use. Here, we provide an improved and simplified data analysis method by adopting binomial and Poisson statistics. METHODS ...