Background: Obesity is a very common disorder resulting from an imbalance between food intake and energy expenditure, and it has a substantial impact on the development of chronic diseases.  The aim of this study was to examine the association of INSIG2 (rs7566605) gene polymorphism with obesity and obesity associated phenotypes in North Indian subjects. Methods: The variants were investig...

background: obesity associated with type 2 diabetes, and hypertension increased mortality and morbidity. glutamate decarboxylase 2 (gad2) gene is associated with obesity and it regulate food intake and insulin level. we investigated the association of gad-2gene −243a>g (rs2236418) and +61450c>a (rs992990) polymorphisms with obesity and related phenotypes. methods: insulin, glucose and lipid lev...

The hormonal responses to anaesthesia and cardiac surgery were studied in 20 patients. Ten patients were anaesthetized with fentanyl 60 microgram kg-1 and nitrous oxide in oxygen and 10 with etomidate 0.3 mgkg-1 and nitrous oxide in oxygen plus halothane. There were no significant changes in cortisol, growth hormone or insulin concentrations in response to surgery in either group, although cort...

Home / Archives Vol. 8 No. 2 (2022): July Research Article THE COMBINATION OF HIGH FAT DIET AND MONOSODIUM GLUTAMATE ALTERING ADIPOGENESIS, BRAIN RESISTIN SERUM CORTISOL LEVEL IN FEMALE RAT Authors Aris Widayati Department of Physiology, Faculty Medicine, Universitas Brawijaya, Malang, Indonesia Dewi Mustika Yhusi Karina Riskawati Agustin Iskandar Parasitology, Nia Kurnianingsih DOI: https://do...

Glucocorticoids contribute to obesity and metabolic syndrome; however, the mechanisms are unclear, and prognostic measures are unavailable. A systems level understanding of the hypothalamic-pituitary-adrenal (HPA)-leptin axis may reveal novel insights. Eighteen obese premenopausal women provided blood samples every 10 min over 24 h, which were assayed for cortisol, adrenocorticotropin releasing...

Background: Acute intoxication with ALP is extremely lethal. The present study was conducted to determine the range of serum cortisol levels in ALP poisoning and its correlation with patient outcome. Methods: This study was carried out on patients who were intoxicated with ALP. Their demographic data and pertinent findings in their history and physical examination were recorded at the time o...

Abdominal obesity has been suggested to be associated with perturbations of the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. In a population of 51-yr-old men (n = 284) salivary cortisol concentrations were determined on repeated (n = 7) occasions over a random working day, and perceived stress was reported in parallel. Cortisol values were then related to reported stress (stress...

background: polycystic ovary syndrome (pcos) is highly associated with non-alcoholic fatty liver disease (nafld). there are extensive ethnic differences in the clinical manifestations, pathological changes, and ovarian changes in women with pcos. objective: to investigate the prevalence and clinical characteristics of nafld in chinese women with pcos. materials and methods: non-pregnant women w...

Background and Aim: Stress has been associated with recurrent aphthous stomatitis (RAS). The common treatment of RAS is a topical steroid. This study aimed to investigate the difference of salivary cortisol between RAS patients treated with a topi-cal steroid and those without treatment. Materials and Methods: Thirty-two female patients with RAS participated in this case-control study and were...