نتایج جستجو برای: alteplase

تعداد نتایج: 6831  

2017
Bruce C. V. Campbell Peter J. Mitchell Leonid Churilov Mahsa Keshtkaran Keun-Sik Hong Timothy J. Kleinig Helen M. Dewey Nawaf Yassi Bernard Yan Richard J. Dowling Mark W. Parsons Teddy Y. Wu Mark Brooks Marion A. Simpson Ferdinand Miteff Christopher R. Levi Martin Krause Timothy J. Harrington Kenneth C. Faulder Brendan S. Steinfort Timothy Ang Rebecca Scroop P. Alan Barber Ben McGuinness Tissa Wijeratne Thanh G. Phan Winston Chong Ronil V. Chandra Christopher F. Bladin Henry Rice Laetitia de Villiers Henry Ma Patricia M. Desmond Atte Meretoja Dominique A. Cadilhac Geoffrey A. Donnan Stephen M. Davis

Background Endovascular thrombectomy improves functional outcome in large vessel occlusion ischemic stroke. We examined disability, quality of life, survival and acute care costs in the EXTEND-IA trial, which used CT-perfusion imaging selection. Methods Large vessel ischemic stroke patients with favorable CT-perfusion were randomized to endovascular thrombectomy after alteplase versus altepla...

Journal: :Journal of the Royal Society of Medicine 1996

Journal: :Brain and neurological disorders 2022

Introduction and aim: Hemorrhagic transformation (HT) is the most feared complication in acute phase of ischemic stroke. Predicting HT utmost importance clinical practice. In latest years a lot prediction scores have been proposed, but their comparison real life lack. Therefore, aim our study was to provide information about this topic. Materials Methods: We retrospectively calculated THRIVE, S...

Journal: :Archives of internal medicine 2007
Daniella J Perlroth Gillian D Sanders Michael K Gould

BACKGROUND Thrombolytic therapy is controversial in patients with submassive pulmonary embolism. METHODS We performed a cost-effectiveness analysis to compare health effects and costs of treatment with alteplase plus heparin sodium vs heparin alone in hemodynamically stable patients with pulmonary embolism and right ventricular dysfunction by developing a Markov model and using data from clin...

Journal: :Cerebrovascular diseases 2013
Eva Giralt-Steinhauer Ana Rodríguez-Campello Elisa Cuadrado-Godia Ángel Ois Jordi Jiménez-Conde Carolina Soriano-Tárraga Jaume Roquer

BACKGROUND Intravenous (i.v.) thrombolysis within 4.5 h of symptom onset has proven efficacy in acute ischemic stroke treatment, although half of all outcomes are unfavorable. The recently published DRAGON score aims to predict the 3-month outcome in stroke patients who have received i.v. alteplase. The purpose of this study was an external validation of the results of the DRAGON score in a Spa...

Journal: :Journal of the Neurological Sciences 2019

Journal: :Stroke 2021

Background and Purpose: Accumulating evidence from randomized controlled clinical trials suggests that tenecteplase may represent an effective treatment alternative to alteplase for acute ischemic stroke. In the present systematic review meta-analysis, we sought compare efficacy safety outcomes of intravenous administration stroke patients with large vessel occlusions (LVOs). Methods: We search...

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