نتایج جستجو برای: alteplase
تعداد نتایج: 6831 فیلتر نتایج به سال:
Background Endovascular thrombectomy improves functional outcome in large vessel occlusion ischemic stroke. We examined disability, quality of life, survival and acute care costs in the EXTEND-IA trial, which used CT-perfusion imaging selection. Methods Large vessel ischemic stroke patients with favorable CT-perfusion were randomized to endovascular thrombectomy after alteplase versus altepla...
Introduction and aim: Hemorrhagic transformation (HT) is the most feared complication in acute phase of ischemic stroke. Predicting HT utmost importance clinical practice. In latest years a lot prediction scores have been proposed, but their comparison real life lack. Therefore, aim our study was to provide information about this topic. Materials Methods: We retrospectively calculated THRIVE, S...
BACKGROUND Thrombolytic therapy is controversial in patients with submassive pulmonary embolism. METHODS We performed a cost-effectiveness analysis to compare health effects and costs of treatment with alteplase plus heparin sodium vs heparin alone in hemodynamically stable patients with pulmonary embolism and right ventricular dysfunction by developing a Markov model and using data from clin...
BACKGROUND Intravenous (i.v.) thrombolysis within 4.5 h of symptom onset has proven efficacy in acute ischemic stroke treatment, although half of all outcomes are unfavorable. The recently published DRAGON score aims to predict the 3-month outcome in stroke patients who have received i.v. alteplase. The purpose of this study was an external validation of the results of the DRAGON score in a Spa...
Background and Purpose: Accumulating evidence from randomized controlled clinical trials suggests that tenecteplase may represent an effective treatment alternative to alteplase for acute ischemic stroke. In the present systematic review meta-analysis, we sought compare efficacy safety outcomes of intravenous administration stroke patients with large vessel occlusions (LVOs). Methods: We search...
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